Journal of Pharmacology and Experimental Therapeutics: 249 (2)

May 01, 1989; Volume 249,Issue 2

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Trifenagrel: a chemically novel platelet aggregation inhibitor.
S L Abrahams, R J Hazen, A G Batson and A P Phillips

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 359-365;
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Cyclooxygenase inhibition unmasks the full antidiuretic agonist activity of the vasopressin antagonist, SK&F 101926, in dogs.
C R Albrightson-Winslow, N Caldwell, D P Brooks, W F Huffman, F L Stassen and L B Kinter

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 366-371;
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Pharmacokinetics and pharmacodynamics of atrial natriuretic peptide after bolus and infusion administration in the isolated perfused rat kidney.
M E Brier and G B Harding

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 372-377;
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Plasma protein binding of flurbiprofen: enantioselectivity and influence of pathophysiological status.
M P Knadler, D C Brater and S D Hall

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 378-385;
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Differential cross-tolerance to opioid agonists in morphine-tolerant pigeons responding under a schedule of food presentation.
R M Craft, M J Picker and L A Dykstra

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 386-393;
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Phosphodiesterase isozyme inhibition and the potentiation by zaprinast of endothelium-derived relaxing factor and guanylate cyclase stimulating agents in vascular smooth muscle.
A L Harris, B M Lemp, R G Bentley, M H Perrone, L T Hamel and P J Silver

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 394-400;
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Unsurmountable antagonism to 5-hydroxytryptamine in rat kidney results from pseudoirreversible inhibition rather than multiple receptors or allosteric receptor modulation.
R A Bond, A G Ornstein and D E Clarke

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 401-410;
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In vivo metabolism of atrial natriuretic peptide: identification of plasma metabolites and enzymes responsible for their generation.
P A Krieter, G M Olins, S P Verrett and R C Durley

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 411-417;
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Benzodiazepine and beta-carboline interactions with GABAA receptor-gated chloride channels in mammalian cultured spinal cord neurons.
A K Mehta and M K Ticku

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 418-423;
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Cysteamine produces dose-related bidirectional immunomodulatory effects in mice.
H U Bryant, J W Holaday and E W Bernton

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 424-429;
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The bronchopulmonary pharmacology of SK&F 104353 in anesthetized guinea pigs: demonstration of potent and selective antagonism of responses to peptidoleukotrienes.
T J Torphy, J F Newton, M A Wasserman, L Vickery-Clark, R R Osborn, L S Bailey, L A Yodis, D C Underwood and D W Hay

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 430-437;
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Pentobarbital-like discriminative stimulus effects of N-methyl-D-aspartate antagonists.
J Willetts and R L Balster

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 438-443;
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Psychoactive cannabinoids reduce gastrointestinal propulsion and motility in rodents.
J E Shook and T F Burks

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 444-449;
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Effect of 1,3-bis-(2-chloroethyl)-1-nitrosourea on cholephilic dye metabolism and excretion in anesthetized rats.
D Hoyt and R E Larson

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 450-455;
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Sensitivity and tolerance to ethanol-induced hypothermia in genetically selected mice.
J C Crabbe, D J Feller and J S Dorow

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 456-461;
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Differential modulation by [D-Pen2, D-Pen5]enkephalin and dynorphin A-(1-17) of the inhibitory bladder motility effects of selected mu agonists in vivo.
R J Sheldon, L Nunan and F Porreca

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 462-469;
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Kinins contribute to the contractile effects of rat glandular kallikrein on the isolated rat uterus.
G G Orce, O A Carretero, G Scicli and A G Scicli

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 470-475;
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Stereoselective uptake of atenolol into storage granules isolated from PC12 cells.
E E Bagwell, J G Webb, T Walle and T E Gaffney

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 476-482;
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Effects of acute and chronic acyclovir on canine renal function.
A S Kimes, K Kumor, K McCullough, D Holtzclaw, D Teller, D Dobyan and D Spector

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 483-491;
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Effects of protein kinase inhibitor, 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine, on beta-2 adrenergic receptor activation and desensitization in intact human lymphocytes.
K K Hui and J L Yu

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 492-498;
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Arginine8-vasopressin reduces spinal cord blood flow after spinal subarachnoid injection in rats.
J B Long, A Martinez-Arizala, S H Johnson and J W Holaday

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 499-506;
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Effect of continuous exposure to selective D1 and D2 dopaminergic agonists on rotational behavior in supersensitive mice.
J D Winkler and B Weiss

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 507-516;
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Mechanistic studies of the metabolic chiral inversion of (R)-ibuprofen in humans.
T A Baillie, W J Adams, D G Kaiser, L S Olanoff, G W Halstead, H Harpootlian and G J Van Giessen

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 517-523;
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Cyclic GMP: a potential mediator of neurally- and drug-induced relaxation of opossum lower esophageal sphincter.
M Barnette, T J Torphy, M Grous, C Fine and H S Ormsbee

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 524-528;
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Alpha adrenoceptor agonist stimulation of oxygen consumption in rat proximal and distal nephrons.
F A Gesek and J W Strandhoy

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 529-534;
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Characterization of serotonin-1B receptors negatively coupled to adenylate cyclase in OK cells, a renal epithelial cell line from the opossum.
T J Murphy and D B Bylund

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 535-543;
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Novel peptidic mu opioid antagonists: pharmacologic characterization in vitro and in vivo.
T H Kramer, J E Shook, W Kazmierski, E A Ayres, W S Wire, V J Hruby and T F Burks

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 544-551;
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Prophylaxis of cyanobacterial and mushroom cyclic peptide toxins.
W H Adams, R D Stoner, D G Adams, H Read, D N Slatkin and H W Siegelman

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 552-556;
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Discriminative stimulus effects of mu and kappa opioids in the pigeon: analysis of the effects of full and partial mu and kappa agonists.
M J Picker and L A Dykstra

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 557-566;
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Characterization of the pharmacokinetic interaction between nifedipine and ethanol in the rat.
K M Boje and H L Fung

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 567-571;
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Pharmacological characterization of neural mechanisms regulating mucosal ion transport in mouse jejunum.
R J Sheldon, M E Malarchik, D A Fox, T F Burks and F Porreca

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 572-582;
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Human fat cell alpha-2 adrenoceptors. I. Functional exploration and pharmacological definition with selected alpha-2 agonists and antagonists.
J Galitzky, P Mauriege, M Berlan and M Lafontan

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 583-591;
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Human fat cell alpha-2 adrenoceptors. II. Comparative study of partial and full agonist binding parameters using [3H]clonidine and [3H]UK-14,304.
J Galitzky, M Lafontan, H Paris and M Berlan

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 592-600;
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Pharmacokinetic modeling of the anticonvulsant action of phenobarbital in rats.
J Dingemanse, J B van Bree and M Danhof

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 601-608;
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Inhibition of converting enzyme in the cerebrospinal fluid of rats after oral treatment with converting enzyme inhibitors.
P Gohlke, H Urbach, B Schölkens and T Unger

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 609-616;
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Mexiletine-quinidine combination: enhanced antiarrhythmic and electrophysiologic activity in the dog.
H J Duff

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 617-622;
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Activation of heart sarcoplasmic reticulum Ca++-stimulated adenosine triphosphatase by insulin.
M P Gupta, S L Lee and N S Dhalla

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 623-630;
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Metabolic changes in glutathione and metallothionein in newborn rat liver.
K R Gallant and M G Cherian

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 631-637;
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Influence of enzyme induction and inhibition on the oxidation of nifedipine, sparteine, mephenytoin and antipyrine in humans as assessed by a "cocktail" study design.
J H Schellens, J H van der Wart, M Brugman and D D Breimer

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 638-645;
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Interaction of 8-(N,N-diethylamino)octyl 3,4,5-trimethoxybenzoate hydrochloride, ryanodine and procaine with muscarinic cholinergic M2 receptor sites in smooth muscle.
T Hisayama, I Takayanagi, N Kumagai and H Kubo

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 646-651;
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Modulation of pyloric motor activity via adrenergic receptors.
H D Allescher, S Ahmad, F Kostolanska, C Y Kwan and E E Daniel

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 652-659;
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Catechol and indole metabolism in rostral ventrolateral medulla change synchronously with changing blood pressure.
D Bhaskaran and C R Freed

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 660-666;
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Potentiation of 3-methylcholanthrene induction of rat hepatic cytochrome P450IA1 by dexamethasone in vivo.
A J Sherratt, D E Banet, M W Linder and R A Prough

Journal of Pharmacology and Experimental Therapeutics May 1989, 249 (2) 667-672;

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