Journal of Pharmacology and Experimental Therapeutics: 245 (3)

June 01, 1988; Volume 245,Issue 3

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Mechanism of action of minoxidil sulfate-induced vasodilation: a role for increased K+ permeability.
K D Meisheri, L A Cipkus and C J Taylor

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 751-760;
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Sustained high release at rapid stimulation rates and reduced functional autoreceptors characterize prefrontal cortex dopamine terminals.
I S Hoffmann, R K Talmaciu, C P Ferro and L X Cubeddu

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 761-772;
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5-Hydroxytryptamine antagonist ICS 205-930 blocks cardiac potassium, sodium and calcium currents.
G Scholtysik, Y Imoto, A Yatani and A M Brown

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 773-778;
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Vasopressin inhibits sympathetic ganglionic transmission but potentiates sympathetic neuroeffector responses in hindlimb vasculature of rabbits.
K P Patel and P G Schmid

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 779-785;
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Characterization of [5,6-3H]SQ 29,548 as a high affinity radioligand, binding to thromboxane A2/prostaglandin H2-receptors in human platelets.
A Hedberg, S E Hall, M L Ogletree, D N Harris and E C Liu

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 786-792;
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Activation of alpha-1 adrenoreceptors of rat aorta by analogs of imidazoline.
V K Lamba-Kanwal, A Hamada, A Adejare, M T Clark, D D Miller and P N Patil

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 793-797;
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Effects of age on neurotransmission at the cardiac sympathetic neuroeffector junction.
R N Daly, P B Goldberg and J Roberts

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 798-803;
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Effects of N-deacetylation and N-desulfation of heparin on its anticoagulant activity and in vivo disposition.
T D Bjornsson, D E Schneider and A R Hecht

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 804-808;
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Nonlinear pharmacokinetics of aspirin in rats.
M G Wientjes and G Levy

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 809-815;
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Brain uptake of benzodiazepines: effects of lipophilicity and plasma protein binding.
D R Jones, S D Hall, E K Jackson, R A Branch and G R Wilkinson

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 816-822;
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Effects of phenothiazines on the Na+-H+ exchanger of the brush-border membrane from the proximal small intestine of the rabbit.
Y Miyamoto, D F Balkovetz, V Ganapathy, T Iwatsubo, M Hanano and F H Leibach

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 823-828;
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Pharmacology of SCH 34826, an orally active enkephalinase inhibitor analgesic.
R E Chipkin, J G Berger, W Billard, L C Iorio, R Chapman and A Barnett

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 829-838;
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Myotropic activity of leukotriene B4 on lung parenchyma strips is not necessarily attributable to thromboxane A2 release.
F A Fitzpatrick and C F Lawson

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 839-844;
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Oxidative metabolism of hexobarbital in human liver: relationship to polymorphic S-mephenytoin 4-hydroxylation.
R G Knodell, R K Dubey, G R Wilkinson and F P Guengerich

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 845-849;
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Effects of the novel dopamine beta-hydroxylase inhibitor SK&F 102698 on catecholamines and blood pressure in spontaneously hypertensive rats.
B A Berkowitz, A J Arleth, C P Sung, L I Kruse, W E DeWolf and E H Ohlstein

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 850-857;
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MPP+-induced efflux of dopamine and lactate from rat striatum have similar time courses as shown by in vivo brain dialysis.
H Rollema, W G Kuhr, G Kranenborg, J De Vries and C Van den Berg

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 858-866;
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Use of pharmacologic antagonists to deduce commonalities of biologic activity among clostridial neurotoxins.
L L Simpson

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 867-872;
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Elevation of serum prolactin and corticosterone concentrations in the rat after the administration of 3,4-methylenedioxymethamphetamine.
J F Nash, H Y Meltzer and G A Gudelsky

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 873-879;
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Effects of Ro15-4513 and other benzodiazepine receptor inverse agonists on alcohol-induced intoxication in the rat.
P D Suzdak, S M Paul and J N Crawley

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 880-886;
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Inhibition by ranitidine of acetaminophen conjugation and its possible role in ranitidine potentiation of acetaminophen-induced hepatotoxicity.
S A Rogers, K C Gale, J F Newton, J G Dent and T B Leonard

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 887-894;
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Alcohol effects on naloxone-stimulated luteinizing hormone, follicle-stimulating hormone and prolactin plasma levels in female rhesus monkeys.
N K Mello, J H Mendelson, M P Bree and A Skupny

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 895-904;
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Mechanisms of effects of intrathecal serotonin on nociception and blood pressure in rats.
R E Solomon and G F Gebhart

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 905-912;
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Morphine pellet-induced immunomodulation in mice: temporal relationships.
H U Bryant, E W Bernton and J W Holaday

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 913-920;
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Comparison of uptake of dopamine in rat striatal chopped tissue and synaptosomes.
J A Near, J C Bigelow and R M Wightman

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 921-927;
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Aluminum uptake by the in situ rat gut preparation.
S D Provan and R A Yokel

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 928-931;
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Effects of an alpha-2 adrenoceptor agonist on angiotensin converting enzyme inhibitor-induced hypotension and potentiated allergen-evoked inflammatory skin responses.
B R Lindgren, N Grundström and R G Andersson

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 932-935;
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Beta adrenoceptors in the canine large coronary arteries: beta-1 adrenoceptors predominate in vasodilation.
T Nakane, G Tsujimoto, K Hashimoto and S Chiba

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 936-943;
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Presynaptic autoinhibition of central noradrenaline release in vitro: operational characteristics and effects of drugs acting at alpha-2 adrenoceptors in the presence of uptake inhibition.
B Valenta, H Drobny and E A Singer

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 944-949;
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Inhibition of tissue angiotensin converting enzyme by perindopril: in vivo assessment in the rat using radioinhibitor binding displacement.
B Jackson, R B Cubela and C I Johnston

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 950-955;
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Drug metabolite toxicity assessed in human lymphocytes with a purified, reconstituted cytochrome P-450 system.
J S Leeder, M Cannon, A Nakhooda and S P Spielberg

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 956-962;
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Pharmacokinetic patterns of repeated administration of antidepressants in animals. I. Implications for antinociceptive action of clomipramine in mice.
A Eschalier, J Fialip, O Varoquaux, M C Makambila, H Marty and P Bastide

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 963-968;
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MK-801, a proposed noncompetitive antagonist of excitatory amino acid neurotransmission, produces phencyclidine-like behavioral effects in pigeons, rats and rhesus monkeys.
W Koek, J H Woods and G D Winger

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 969-974;
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Liver extraction of vitamin D3 is independent of its hepatic venous or arterial route of delivery. Studies in isolated-perfused rat liver preparations.
M Gascon-Barré, P M Huet, G St-Onge-Brault, A Brault and I Kassissia

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 975-981;
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Effects of chronic treatment with trihexyphenidyl and carbamazepine alone or in combination with haloperidol on substance P content in rat brain: a possible implication of substance P in affective disorders.
H Mitsushio, M Takashima, N Mataga and M Toru

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 982-989;
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Cholinergic transmission in the superior cervical ganglion reinnervated by peripheral vagal stump cut below the nodose ganglion in cats.
T Okamoto, K Kurahashi and M Fujiwara

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 990-994;
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[D-Pro10]-dynorphin(1-11) is a kappa-selective opioid analgesic in mice.
J E Gairin, R Gout, J C Meunier and J Cros

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 995-1001;
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Local actions of trimebutine maleate in canine small intestine.
E E Daniel, F Kostolanska, H D Allescher, S Ahmad and J E Fox

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 1002-1009;
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ICI 169,369 is both a competitive antagonist and an allosteric activator of the arterial 5-hydroxytryptamine2 receptor system.
A J Kaumann and M Frenken

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 1010-1015;
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Inhibition of norepinephrine contractions by diltiazem on aorta and pulmonary artery from young and aged rats: influence of alpha-adrenoceptor reserve.
J C Wanstall and S R O'Donnell

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 1016-1020;
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Biologic response to chronic blockade of vasopressin receptors in Sprague-Dawley rats.
S C Mah, J R Opperman, H P Baum and K G Hofbauer

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 1021-1027;
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Evaluation of the pharmacologic properties of a vasopressin antagonist in Brattleboro rats.
S C Mah and K G Hofbauer

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 1028-1032;
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In vivo interaction of zolpidem with central benzodiazepine (BZD) binding sites (as labeled by [3H]Ro 15-1788) in the mouse brain. Preferential affinity of zolpidem for the omega 1 (BZD1) subtype.
J Benavides, B Peny, A Dubois, G Perrault, E Morel, B Zivkovic and B Scatton

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 1033-1041;
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Phorbol ester modulation of cyclic AMP accumulation in a primary culture of rat aortic smooth muscle cells.
S Phaneuf, P Berta, L P Peuch, J Haiech and J C Cavadore

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 1042-1047;
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Adverse pregnancy outcome in the monkey (Macaca fascicularis) after chronic caffeine exposure.
S G Gilbert, D C Rice, K R Reuhl and B Stavric

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 1048-1053;
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The mitochondrial respiratory toxicity of cephalosporin antibiotics. An inhibitory effect on substrate uptake.
B M Tune, R K Sibley and C Y Hsu

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 1054-1059;
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Classification of bovine aortic alpha-1 adrenoceptors by the criteria of ligand affinity and molecular mass.
S M Shreeve

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 1060-1067;
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Neural modulation of the stimulatory regulatory protein of adenylate cyclase in rat brown adipose tissue.
J G Granneman and R G MacKenzie

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 1068-1074;
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Norepinephrine infusions increase adenylate cyclase responsiveness in brown adipose tissue.
J G Granneman

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 1075-1080;
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Phencyclidine receptor ligands attenuate cortical neuronal injury after N-methyl-D-aspartate exposure or hypoxia.
M P Goldberg, V Viseskul and D W Choi

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 1081-1087;
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Essential fatty acid deficiency reduces the inflammatory cell invasion in rabbit hydronephrosis resulting in suppression of the exaggerated eicosanoid production.
S M Spaethe, M S Freed, K De Schryver-Kecskemeti, J B Lefkowith and P Needleman

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 1088-1094;
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Amphetamine injection into the ventral mesencephalon sensitizes rats to peripheral amphetamine and cocaine.
P W Kalivas and B Weber

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 1095-1102;
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Metabolic basis for a drug hypersensitivity: antibodies in sera from patients with halothane hepatitis recognize liver neoantigens that contain the trifluoroacetyl group derived from halothane.
J G Kenna, H Satoh, D D Christ and L R Pohl

Journal of Pharmacology and Experimental Therapeutics June 1988, 245 (3) 1103-1109;

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