Journal of Pharmacology and Experimental Therapeutics: 244 (1)

January 01, 1988; Volume 244,Issue 1

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Comparison of serotonergic receptor subtypes on the smooth muscle and endothelium of the canine coronary artery.
D S Houston and P M Vanhoutte

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 1-10;
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Enhanced endogenous neurotransmitter overflow in the isolated perfused rat kidney after chronic epinephrine administration: lack of a prejunctional beta adrenoceptor influence.
D D Schwartz and D C Eikenburg

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 11-18;
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Effect of 17 beta-estradiol on endothelium-dependent responses in the rabbit.
V Gisclard, V M Miller and P M Vanhoutte

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 19-22;
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Comparison of nasal, rectal, buccal, sublingual and intramuscular insulin efficacy and the effects of a bile salt absorption promoter.
B J Aungst, N J Rogers and E Shefter

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 23-27;
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An investigation of the antinociceptive activity of calcitonin gene-related peptide alone and in combination with morphine: correlation to 45Ca++ uptake by synaptosomes.
S P Welch, C W Cooper and W L Dewey

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 28-33;
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Evaluation of antagonists of the discriminative stimulus and response rate effects of phencyclidine.
P M Beardsley and R L Balster

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 34-40;
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Regulation of [3H]phorbol-12,13-dibutyrate binding sites in mouse neuroblastoma cells: simultaneous down-regulation by phorbol esters and desensitization of their inhibition of muscarinic receptor function.
W S Lai and E E el-Fakahany

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 41-50;
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Ketamine- and morphine-induced analgesia and catalepsy. I. Tolerance, cross-tolerance, potentiation, residual morphine levels and naloxone action in the rat.
W D Winters, A J Hance, G G Cadd, D D Quam and J L Benthuysen

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 51-57;
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Inhibition of climbing and mossy fiber input to mouse cerebellar Purkinje cells by cholecystokinin.
P L Wood, D J Steel, H S Kim, B Petrack and C A Altar

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 58-62;
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Spinal infusion of opiate and alpha-2 agonists in rats: tolerance and cross-tolerance studies.
C W Stevens, M S Monasky and T L Yaksh

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 63-70;
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Functional antagonism by salbutamol suggests differences in the relative efficacies and dissociation constants of the peptidoleukotrienes in guinea pig trachea.
D W Hay, R M Muccitelli, K A Wilson, M A Wasserman and T J Torphy

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 71-78;
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Persistent reversal of tolerance to anticonvulsant effects and GABAergic subsensitivity by a single exposure to benzodiazepine antagonist during chronic benzodiazepine administration.
S F Gonsalves and D W Gallager

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 79-83;
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Inhibitory effects of diltiazem on vasoconstrictor responses in the cat.
P J Kadowitz, W M Armstead, P Y Roland, A L Hyman and H L Lippton

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 84-90;
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Species variation in toxication and detoxication of acetaminophen in vivo: a comparative study of biliary and urinary excretion of acetaminophen metabolites.
Z Gregus, C Madhu and C D Klaassen

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 91-99;
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Effects of prolonged phenylephrine infusion on cardiac adrenoceptors and calcium channels.
P J Gengo, N Bowling, V L Wyss and J S Hayes

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 100-105;
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Preclinical pharmacology of a new serotonergic receptor antagonist, LY281067.
M L Cohen, R W Fuller, K D Kurz, C J Parli, N R Mason, D B Meyers, J K Smallwood and R E Toomey

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 106-112;
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Toxicity of H2-receptor antagonists to isolated rat hepatocytes: structure-activity relationships.
G F Rush, D Alberts, S Lupo, L A Yodis, T H Brown and G J Durant

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 113-117;
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Role of dapsone hydroxylamine in dapsone-induced hemolytic anemia.
S J Grossman and D J Jollow

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 118-125;
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Acute physical dependence in man: effects of naloxone after brief morphine exposure.
W K Bickel, M L Stitzer, I A Liebson and G E Bigelow

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 126-132;
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Substance P and vasoactive intestinal peptide degradation by mast cell tryptase and chymase.
G H Caughey, F Leidig, N F Viro and J A Nadel

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 133-137;
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The role of prostanoids in the mediation of responses to KC-404, a novel cerebrovasodilator.
W M Armstead, R Mirro, C W Leffler and D W Busija

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 138-143;
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Application of [125I]iodocyanopindolol to measure 5-hydroxytryptamine1B receptors in the brain of the rat.
S J Offord, G A Ordway and A Frazer

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 144-153;
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The serotonin/norepinephrine-link in brain. II. Role of serotonin in the regulation of beta adrenoceptors in the low agonist affinity conformation.
D D Gillespie, D H Manier, E Sanders-Bush and F Sulser

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 154-159;
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Characterization of the functional antagonism and antihypertensive activity displayed by a monoclonal antibody to angiotensin II.
T M Reilly, P C Wong, W A Price and P B Timmermans

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 160-165;
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Do sympathetic neurons coordinate cellular development in the heart and kidney? Effects of neonatal central and peripheral catecholaminergic lesions on cardiac and renal nucleic acids and proteins.
T A Slotkin, B Levant, L Orband-Miller, K L Queen and S Stasheff

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 166-172;
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Beta-2 adrenergic responses to tulobuterol in airway smooth muscle, vascular smooth muscle and adrenergic nerves.
F Ruff, J F Zander, Y Edoute, M C Santais, N A Flavahan, T J Verbeuren and P M Vanhoutte

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 173-180;
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Pharmacological evidence that endothelium-derived relaxing factor is nitric oxide: use of pyrogallol and superoxide dismutase to study endothelium-dependent and nitric oxide-elicited vascular smooth muscle relaxation.
L J Ignarro, R E Byrns, G M Buga, K S Wood and G Chaudhuri

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 181-189;
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Endogenous adenosine modulates gastric acid secretion to histamine in canine parietal cells.
J G Gerber and N A Payne

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 190-194;
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Evidence for the delivery of narcotic antagonists to the colon as their glucuronide conjugates.
J W Simpkins, M Smulkowski, R Dixon and R Tuttle

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 195-205;
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Classification of phenoxybenzamine/prazosin-resistant contractions of rat spleen to norepinephrine by Schild analysis: similarities and differences to postsynaptic alpha-2 adrenoceptors.
T P Kenakin and P J Novak

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 206-212;
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Effects of selected muscarinic cholinergic antagonists on [3H]acetylcholine release from rat hippocampal slices.
R Pohorecki, R Head and E F Domino

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 213-217;
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Desensitization of adenosine and dopamine receptors in rat brain after treatment with adenosine analogs.
N M Porter, M Radulovacki and R D Green

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 218-225;
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High efficiency coupling of alpha-1 adrenergic receptors to inositol phospholipid metabolism revealed by denervation of rat vas deferens.
K P Minneman, G K Mumford and P W Abel

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 226-230;
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Pharmacodynamic model of tolerance: application to nicotine.
H C Porchet, N L Benowitz and L B Sheiner

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 231-236;
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Differential antagonism by naltrexone of the effects of opioids on a fixed-ratio discrimination in rats.
J M Moerschbaecher, C Devia and C Brocklehurst

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 237-246;
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Intravenous clonidine produces hypoxemia by a peripheral alpha-2 adrenergic mechanism.
J C Eisenach

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 247-252;
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Cross-tolerance and cross-sensitization between morphine analgesia and naloxone-sensitive and cimetidine-sensitive stress-induced analgesia.
I J Weinstein, L B Hough and K R Gogas

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 253-258;
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Evaluation of the in vivo dose-response relationship of immunosuppressive drugs using a mouse heart transplant model: application to cyclosporine.
G Babany, R E Morris, I Babany and R E Kates

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 259-262;
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Conjugative clearance of 1-naphthol and disposition of its glucuronide and sulfate conjugates in the isolated perfused rat kidney.
F A Redegeld, G A Hofman and J Noordhoek

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 263-267;
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Mechanisms for the hepatic uptake of organic cations. Studies with the muscle relaxant vecuronium in isolated rat hepatocytes.
W E Mol, G N Fokkema, B Weert and D K Meijer

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 268-275;
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The endothelium inhibits the penetration of serotonin and norepinephrine in the isolated canine saphenous vein.
T J Verbeuren, F H Jordaens, H Bult and A G Herman

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 276-282;
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Differential response of normal and cirrhotic liver to vasoactive agents. A study in the isolated perfused rat liver.
F Ballet, Y Chretien, C Rey and R Poupon

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 283-289;
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Effects of cytochalasin-B and phloretin on digitalis inotropy.
A Ogbaghebriel and P E Dresel

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 290-296;
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Endothelium-dependent and independent responses to prostaglandin H2 and arachidonic acid in isolated dog cerebral arteries.
N Toda, S Inoue, K Bian and T Okamura

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 297-302;
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Inhibition of enkephalin degradation attenuated stress-induced motor suppression (conditioned suppression of motility).
T Nabeshima, A Katoh and T Kameyama

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 303-309;
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Identification of nonserotonergic [3H]ketanserin binding sites associated with nerve terminals in rat brain and with platelets; relation with release of biogenic amine metabolites induced by ketanserin- and tetrabenazine-like drugs.
J E Leysen, A Eens, W Gommeren, P van Gompel, J Wynants and P A Janssen

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 310-321;
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Mechanism of glyceryl trinitrate-induced vasodilation. I. Relationship between drug biotransformation, tissue cyclic GMP elevation and relaxation of rabbit aorta.
J F Brien, B E McLaughlin, S M Kobus, J H Kawamoto, K Nakatsu and G S Marks

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 322-327;
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Mechanism of glyceryl trinitrate-induced vasodilation. II. Lack of evidence for specific binding of GTN to bovine pulmonary vein.
J H Kawamoto, J F Brien, G S Marks and K Nakatsu

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 328-334;
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Sympathoadrenomedullary system mediation of the prostaglandin E2-induced central inhibition of gastric acid output in rats.
K Yokotani, K Yokotani, Y Okuma and Y Osumi

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 335-340;
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Antagonism by naltrexone of the hypotension and bradycardia induced by alpha-methyldopa in conscious normotensive rats.
P L van Giersbergen and W de Jong

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 341-347;
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Electrophysiological effects of amrinone and milrinone in an isolated canine cardiac tissue model of ischemia and reperfusion.
A Lukas and G R Ferrier

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 348-354;
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Inhibitory effects of aminoglycosides on renal protein phosphorylation by protein kinase C.
M Hagiwara, M Inagaki, K Kanamura, H Ohta and H Hidaka

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 355-360;
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The cysteine protease inhibitor, E-64, stimulates the polarization and locomotor responses of endothelial cells to wounding.
R N Mascardo and G Eilon

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 361-367;
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Acute exposure of the neonatal rat to triethyltin results in persistent changes in neurotypic and gliotypic proteins.
J P O'Callaghan and D B Miller

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 368-378;
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Regional distribution of a Ro5 4864 binding site that is functionally coupled to the gamma-aminobutyric acid/benzodiazepine receptor complex in rat brain.
K W Gee, R E Brinton and B S McEwen

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 379-383;
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Prostaglandins mediate the increased sensitivity of left ventricular reflexes after captopril treatment in conscious dogs.
M J Panzenbeck, W Tan, M A Hajdu and I H Zucker

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 384-390;
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Nalbuphine: an autoradiographic opioid receptor binding profile in the central nervous system of an agonist/antagonist analgesic.
E B De Souza, W K Schmidt and M J Kuhar

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 391-402;
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Stimulation of opiate receptors in the dorsal pontine tegmentum inhibits reflex contraction of the urinary bladder.
R N Willette, S Morrison, H N Sapru and D J Reis

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 403-409;
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Electrophysiological effects of BMY 14802, a new potential antipsychotic drug, on midbrain dopamine neurons in the rat: acute and chronic studies.
S R Wachtel and F J White

Journal of Pharmacology and Experimental Therapeutics January 1988, 244 (1) 410-416;

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