Abstract

1. The local anesthetics, cocain, alypin and apothesin, were studied in regard to their penetration through and absorption from various genito-urinary organs.

2. It was found that these drugs are more or less readily absorbed through the urethra, ureters, pelvis of the kidney, praeputium and vagina.

3. It was found that while the local anesthetics are readily and rapidly absorbed from the urethra, they are very poorly absorbed from the urinary bladder.