Abstract
The effects of exercise on heart rate and blood pressure of three patients with angina pectoris were determined before, during, and after treatment with a potent monoamine oxidase inhibitor, isocarboxazid. The elevated levels of heart rate and blood pressure produced by exercise were significantly reduced in each patient by isocarboxazid therapy. It is postulated that such attenuation of the cardiovascular response to exercise could be responsible for the effectiveness of monoamine oxidase inhibitors in the treatment of angina pectoris in some patients.
Footnotes
- Received February 21, 1962.
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ATTENUATION /OF CARDIOVASCULAR RESPONSES TO EXERCISE AS A POSSIBLE BASIS FOR EFFECTIVENESS OF MONOAMINE OXIDASE INHIBITORS IN ANGINA PECTORIS
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