Abstract
The P:O ratios, oxygen consumption in ADP- or IP-deficient media, and ATPase activity of heart mitochondria isolated from digitoxin or ouabain-poisoned guinea pig were studied.
These mitochondria were found to utilize more oxygen in an ADP- or IP-deficient medium than the control mitochondria.
The respiratory response of these mitochondria to the addition of hexokinase and glucose to the ADP-deficient medium was less than that of the controls. The P:O ratio and ATPase activity were unchanged when compared to the controls.
Footnotes
- Received November 9, 1959.
JPET articles become freely available 12 months after publication, and remain freely available for 5 years.Non-open access articles that fall outside this five year window are available only to institutional subscribers and current ASPET members, or through the article purchase feature at the bottom of the page.
|
Log in using your username and password
Purchase access
You may purchase access to this article. This will require you to create an account if you don't already have one.