Abstract
Attempts to demonstrate the existence of a serotonin complex in suspensions of lysed rabbit platelets have not been successful. However, kinetic studies of serotonin uptake by platelets of normal and reserpine-treated guinea pigs indicate that serotonin is taken up by active transfer. Reserpine appears to act by blocking the active transport.
Norepinephrine and epinephrine, but not bufotenine, can also be taken up in platelets in vitro by a process which is blocked by reserpine.
Footnotes
- Received April 27, 1959.
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