Abstract
Experimental bromide intoxication has been produced in dogs. Most of the classical signs of human intoxication were reproduced. These included neurotoxicity, gastrointestinal toxicity and toxicity to the skin. As is often the case in human intoxication, little relationship was found between the blood bromide level and the first appearance of the physical signs of intoxication. The appearance of emaciation and weight loss on undiminished ingestion of food suggests that bromide may interfere with absorption of nutrients from the gastrointestinal tract.
Footnotes
- Received October 31, 1957.
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