Abstract
1. Ranked in the order of their relative hypotensive potency from greatest to least, the preparations investigated may be arranged as follows: protoveratrine A = germitetrine B = Veralba 〉 protoveratrine B 〉 Unitensen.
2. No dissociation of hypotensive from emetic activity was observed with protoveratrine A, Veralba or Unitensen.
3. Protoveratrine A reduces arterial pressure in the dog by acting upon receptors whose impulses travel to the vasomotor center via the vagi and the carotid sinus nerves.
Footnotes
- Received April 23, 1954.
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