Abstract
1. Critical examination of a recent study claiming to evaluate the Litchfield-Wilcoxon procedure for rapid graphic solution of bioassays based on dose-per cent effect curves revealed the following:
(a) the procedure had been modified in a manner which increased the error by 5-fold over the unmodified method.
(b) the study was based entirely on the use of this modified procedure; therefore, the conclusions do not apply to the Litchfield-Wilcoxon procedure.
2. When the same bioassay problem used in the above-mentioned study was solved by 21 subjects having no previous experience with biostatistics, the Litchfield-Wilcoxon procedure gave estimates which were in satisfactory agreement with the value obtained by probit analysis.
Footnotes
- Received December 1, 1952.
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