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SEP-363856, a Novel Psychotropic Agent with a Unique, Non-D₂ Receptor Mechanism of Action
Nina Dedic, Philip G. Jones, Seth C. Hopkins, Robert Lew, Liming Shao, John E. Campbell, Kerry L. Spear, Thomas H. Large, Una C. Campbell, Taleen Hanania, Emer Leahy and Kenneth S. Koblan

Journal of Pharmacology and Experimental Therapeutics October 2019, 371 (1) 1-14; DOI: https://doi.org/10.1124/jpet.119.260281
Open Access
Stem Cell Therapies in Alzheimer’s Disease: Applications for Disease Modeling
Zizhen Si and Xidi Wang

Journal of Pharmacology and Experimental Therapeutics May 2021, 377 (2) 207-217; DOI: https://doi.org/10.1124/jpet.120.000324
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Cinnabarinic Acid Provides Hepatoprotection Against Nonalcoholic Fatty Liver Disease
Nikhil Y. Patil, Iulia Rus, Emma Downing, Ashok Mandala, Jacob E. Friedman and Aditya D. Joshi

Journal of Pharmacology and Experimental Therapeutics October 2022, 383 (1) 32-43; DOI: https://doi.org/10.1124/jpet.122.001301
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Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity
Jaromir Vlach, Andrew T. Bender, Melinda Przetak, Albertina Pereira, Aditee Deshpande, Theresa L. Johnson, Sonja Reissig, Evgeni Tzvetkov, Djordje Musil, Noune Tahmassian Morse, Philipp Haselmayer, Simone C. Zimmerli, Shinji L. Okitsu, Robert L. Walsky and Brian Sherer

Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 397-409; DOI: https://doi.org/10.1124/jpet.120.000275
Open Access
Assessment of Inhaled Treprostinil Palmitil, Inhaled and Intravenous Treprostinil, and Oral Selexipag in a Sugen/Hypoxia Rat Model of Pulmonary Arterial Hypertension
Michel R. Corboz, Adam J. Plaunt, Vladimir S. Malinin, Zhili Li, Helena Gauani, Donald Chun, David Cipolla, Walter R. Perkins and Richard W. Chapman

Journal of Pharmacology and Experimental Therapeutics October 2022, 383 (1) 103-116; DOI: https://doi.org/10.1124/jpet.122.001174
Open Access
A Novel C-C Chemoattractant Cytokine (Chemokine) Receptor 6 (CCR6) Antagonist (PF-07054894) Distinguishes between Homologous Chemokine Receptors, Increases Basal Circulating CCR6⁺ T Cells, and Ameliorates Interleukin-23-Induced Skin Inflammation
Wei Li, Kimberly K Crouse, Jennifer Alley, Richard K Frisbie, Susan C Fish, Tatyana A Andreyeva, Lori A Reed, Mitchell Thorn, Giovanni DiMaggio, Carol B Donovan, Donald Bennett, Jeonifer Garren, Elias Oziolor, Jesse Qian, Leah Newman, Amanda P Vargas, Steven W Kumpf, Stefan J Steyn, Mark E Schnute, Atli Thorarensen, Martin Hegen, Erin Stevens, Mark Collinge, Thomas A Lanz, Fabien Vincent, Michael S Vincent and Gabriel Berstein

Journal of Pharmacology and Experimental Therapeutics July 2023, 386 (1) 80-92; DOI: https://doi.org/10.1124/jpet.122.001452
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Preclinical Characterization of LY3209590, a Novel Weekly Basal Insulin Fc-Fusion Protein
Julie S. Moyers, Ryan J. Hansen, Jonathan W. Day, Craig D. Dickinson, Chen Zhang, Xiaoping Ruan, Liyun Ding, Robin M. Brown, Hana E. Baker and John M. Beals

Journal of Pharmacology and Experimental Therapeutics September 2022, 382 (3) 346-355; DOI: https://doi.org/10.1124/jpet.122.001105
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Minimal Physiologically Based Pharmacokinetic-Pharmacodynamic (mPBPK-PD) Model of N-Acetylgalactosamine–Conjugated Small Interfering RNA Disposition and Gene Silencing in Preclinical Species and Humans
Vivaswath S. Ayyar, Dawei Song, Songmao Zheng, Thomas Carpenter and Donald L. Heald

Journal of Pharmacology and Experimental Therapeutics November 2021, 379 (2) 134-146; DOI: https://doi.org/10.1124/jpet.121.000805
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Protective Effect of Anwulignan on Gastric Injury Induced by Indomethacin in Mice
Jiawei Liu, Jiahui Fang, Junxiong Zhang, Dan Wang, Zhihong Zhang, Chunmei Wang, Jinghui Sun, Jianguang Chen, He Li and Shu Jing

Journal of Pharmacology and Experimental Therapeutics October 2022, 383 (1) 80-90; DOI: https://doi.org/10.1124/jpet.121.001055
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Molecular Interplay between microRNA-34a and Sirtuin1 in Hyperglycemia-Mediated Impaired Angiogenesis in Endothelial Cells: Effects of Metformin
Gnanapragasam Arunachalam, Arun Prasath Lakshmanan, Samson Mathews Samuel, Chris R. Triggle and Hong Ding

Journal of Pharmacology and Experimental Therapeutics February 2016, 356 (2) 314-323; DOI: https://doi.org/10.1124/jpet.115.226894

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