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In Vitro and In Silico Characterization of Lemborexant (E2006), a Novel Dual Orexin Receptor Antagonist
Carsten Theodor Beuckmann, Michiyuki Suzuki, Takashi Ueno, Kazuya Nagaoka, Tohru Arai and Hiroyuki Higashiyama

Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 287-295; DOI: https://doi.org/10.1124/jpet.117.241422
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Pharmacological Characterization of Apraglutide, a Novel Long-Acting Peptidic Glucagon-Like Peptide-2 Agonist, for the Treatment of Short Bowel Syndrome
Diane M. Hargrove, Sudarkodi Alagarsamy, Glenn Croston, Régent Laporte, Steve Qi, Karthik Srinivasan, Javier Sueiras-Diaz, Kazimierz Wiśniewski, Jennifer Hartwig, Mark Lu, Alexander P. Posch, Halina Wiśniewska, Claudio D. Schteingart, Pierre J.-M. Rivière and Violetta Dimitriadou

Journal of Pharmacology and Experimental Therapeutics May 2020, 373 (2) 193-203; DOI: https://doi.org/10.1124/jpet.119.262238
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NKTR-181: A Novel Mu-Opioid Analgesic with Inherently Low Abuse Potential
Takahiro Miyazaki, Irene Y. Choi, Werner Rubas, Neel K. Anand, Cherie Ali, Juli Evans, Hema Gursahani, Marlene Hennessy, Grace Kim, Daniel McWeeney, Juergen Pfeiffer, Phi Quach, David Gauvin, Timothy A. Riley, Jennifer A. Riggs, Kathleen Gogas, Jonathan Zalevsky and Stephen K. Doberstein

Journal of Pharmacology and Experimental Therapeutics October 2017, 363 (1) 104-113; DOI: https://doi.org/10.1124/jpet.117.243030
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MLi-2, a Potent, Selective, and Centrally Active Compound for Exploring the Therapeutic Potential and Safety of LRRK2 Kinase Inhibition
Matthew J. Fell, Christian Mirescu, Kallol Basu, Boonlert Cheewatrakoolpong, Duane E. DeMong, J. Michael Ellis, Lynn A. Hyde, Yinghui Lin, Carrie G. Markgraf, Hong Mei, Michael Miller, Frederique M. Poulet, Jack D. Scott, Michelle D. Smith, Zhizhang Yin, Xiaoping Zhou, Eric M. Parker, Matthew E. Kennedy and John A. Morrow

Journal of Pharmacology and Experimental Therapeutics December 2015, 355 (3) 397-409; DOI: https://doi.org/10.1124/jpet.115.227587
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Therapeutic Assessment of Combination Therapy with a Neprilysin Inhibitor and Angiotensin Type 1 Receptor Antagonist on Angiotensin II–Induced Atherosclerosis, Abdominal Aortic Aneurysms, and Hypertension
Yasir AlSiraj, Sean E. Thatcher, Ching Ling Liang, Heba Ali, Mark Ensor and Lisa A. Cassis

Journal of Pharmacology and Experimental Therapeutics June 2021, 377 (3) 326-335; DOI: https://doi.org/10.1124/jpet.121.000525
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Inhibiting MicroRNA-29a Protects Myocardial Ischemia-Reperfusion Injury by Targeting SIRT1 and Suppressing Oxidative Stress and NLRP3-Mediated Pyroptosis Pathway
Shoukun Ding, Donghai Liu, Lixia Wang, Guanggong Wang and Yaobin Zhu

Journal of Pharmacology and Experimental Therapeutics January 2020, 372 (1) 128-135; DOI: https://doi.org/10.1124/jpet.119.256982
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Characterization of the Neurochemical and Behavioral Effects of Solriamfetol (JZP-110), a Selective Dopamine and Norepinephrine Reuptake Inhibitor
Michelle G. Baladi, Michael J. Forster, Michael B. Gatch, Richard B. Mailman, Danielle L. Hyman, Lawrence P. Carter and Aaron Janowsky

Journal of Pharmacology and Experimental Therapeutics August 2018, 366 (2) 367-376; DOI: https://doi.org/10.1124/jpet.118.248120
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Pharmacokinetic and Pharmacodynamic Properties of Drug Delivery Systems
Patrick M. Glassman and Vladimir R. Muzykantov

Journal of Pharmacology and Experimental Therapeutics September 2019, 370 (3) 570-580; DOI: https://doi.org/10.1124/jpet.119.257113
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Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
Samuel Obeng, Jenny L. Wilkerson, Francisco León, Morgan E. Reeves, Luis F. Restrepo, Lea R. Gamez-Jimenez, Avi Patel, Anna E. Pennington, Victoria A. Taylor, Nicholas P. Ho, Tobias Braun, John D. Fortner, Morgan L. Crowley, Morgan R. Williamson, Victoria L.C. Pallares, Marco Mottinelli, Carolina Lopera-Londoño, Christopher R. McCurdy, Lance R. McMahon and Takato Hiranita

Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 410-427; DOI: https://doi.org/10.1124/jpet.120.000189
Open Access
AM833 Is a Novel Agonist of Calcitonin Family G Protein–Coupled Receptors: Pharmacological Comparison with Six Selective and Nonselective Agonists
Madeleine M. Fletcher, Peter Keov, Tin T. Truong, Grace Mennen, Caroline A. Hick, Peishen Zhao, Sebastian G.B. Furness, Thomas Kruse, Trine R. Clausen, Denise Wootten and Patrick M. Sexton

Journal of Pharmacology and Experimental Therapeutics June 2021, 377 (3) 417-440; DOI: https://doi.org/10.1124/jpet.121.000567

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