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Journal of Pharmacology and Experimental Therapeutics

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Most read article(s)

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    Yaotian Hu, Wenjing Zhou, Zhiyi Xue, Xuemeng Liu, Zichao Feng, Yulin Zhang, Xiaofei Liu, Wenjie Li, Qing Zhang, Anjing Chen, Bin Huang and Jian Wang
    Journal of Pharmacology and Experimental Therapeutics January 2022, 380 (1) 63-75; DOI: https://doi.org/10.1124/jpet.121.000852
  • You have access
    Discovery and Preclinical Characterization of GSK1278863 (Daprodustat), a Small Molecule Hypoxia Inducible Factor–Prolyl Hydroxylase Inhibitor for Anemia
    Jennifer L. Ariazi, Kevin J. Duffy, David F. Adams, Duke M. Fitch, Lusong Luo, Melissa Pappalardi, Mangatt Biju, Erin Hugger DiFilippo, Tony Shaw, Ken Wiggall and Connie Erickson-Miller
    Journal of Pharmacology and Experimental Therapeutics December 2017, 363 (3) 336-347; DOI: https://doi.org/10.1124/jpet.117.242503
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    Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
    Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333
  • Open Access
    The Dopamine D1 Receptor Positive Allosteric Modulator Mevidalen (LY3154207) Enhances Wakefulness in the Humanized D1 Mouse and in Sleep-Deprived Healthy Male Volunteers
    Andrew P. McCarthy, Kjell A. Svensson, Elaine Shanks, Claire Brittain, Brian J. Eastwood, William Kielbasa, Kevin M. Biglan and Keith A. Wafford
    Journal of Pharmacology and Experimental Therapeutics March 2022, 380 (3) 143-152; DOI: https://doi.org/10.1124/jpet.121.000719
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    Pharmacokinetics and Pharmacodynamic Effects of Nemvaleukin Alfa, a Selective Agonist of the Intermediate-Affinity IL-2 Receptor, in Cynomolgus Monkeys
    Jared E. Lopes, Lei Sun, Heather L. Flick, Erin A. Murphy and Heather C. Losey
    Journal of Pharmacology and Experimental Therapeutics November 2021, 379 (2) 203-210; DOI: https://doi.org/10.1124/jpet.121.000612
  • Open Access
    Pharmacokinetics and Safety Studies in Rodent Models Support Development of EPICERTIN as a Novel Topical Wound-Healing Biologic for Ulcerative Colitis
    Daniel Tusé, Micaela Reeves, Joshua Royal, Krystal T. Hamorsky, Hanna Ng, Maria Arolfo, Carol Green, Abhishek Trigunaite, Toufan Parman, Goo Lee and Nobuyuki Matoba
    Journal of Pharmacology and Experimental Therapeutics March 2022, 380 (3) 162-170; DOI: https://doi.org/10.1124/jpet.121.000904
  • You have access
    Pharmacokinetic and Pharmacodynamic Properties of Drug Delivery Systems
    Patrick M. Glassman and Vladimir R. Muzykantov
    Journal of Pharmacology and Experimental Therapeutics September 2019, 370 (3) 570-580; DOI: https://doi.org/10.1124/jpet.119.257113
  • Open Access
    Nonclinical Characterization of the Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor Roxadustat, a Novel Treatment of Anemia of Chronic Kidney Disease
    Ughetta del Balzo, Pierre E. Signore, Gail Walkinshaw, Todd W. Seeley, Mitchell C. Brenner, Qingjian Wang, Guangjie Guo, Michael P. Arend, Lee A. Flippin, F. Aisha Chow, David C. Gervasi, Christian H. Kjaergaard, Ingrid Langsetmo, Volkmar Guenzler, David Y. Liu, Steve J. Klaus, Al Lin and Thomas B. Neff
    Journal of Pharmacology and Experimental Therapeutics August 2020, 374 (2) 342-353; DOI: https://doi.org/10.1124/jpet.120.265181
  • Open Access
    Protein Kinase A–Mediated Effects of Protein Kinase C Partial Agonist 5-(Hydroxymethyl)Isophthalate 1a3 in Colorectal Cancer Cells
    Ilari Tarvainen, Rebecca C. Nunn, Raimo K. Tuominen, Maria H. Jäntti and Virpi Talman
    Journal of Pharmacology and Experimental Therapeutics January 2022, 380 (1) 54-62; DOI: https://doi.org/10.1124/jpet.121.000848
  • Open Access
    Targeted Drug Delivery to Hepatic Stellate Cells for the Treatment of Liver Fibrosis
    Zhijin Chen, Akshay Jain, Hao Liu, Zhen Zhao and Kun Cheng
    Journal of Pharmacology and Experimental Therapeutics September 2019, 370 (3) 695-702; DOI: https://doi.org/10.1124/jpet.118.256156

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