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Journal of Pharmacology and Experimental Therapeutics

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JPET is Excited to Announce the Addition of "Viewpoints"

ASPET Ends Page Charges for Open Access Articles

Special Section on Non-Coding RNAs in Clinical Practice: From Biomarkers to Therapeutic Tools, freely accessible through June 30, 2023

2021 IMPACT FACTOR 4.402

Call for Papers - Special Section on Nanotechnology-based Delivery Strategies for Protein and Peptide Therapeutics for January 2024

Call for Papers - Special Section on Medical Countermeasures for February 2024

Call for Papers - Special Section on Nanotherapeutics in Cancer Research for March 2024

Call for Papers - Special Section on Quantitative Systems Pharmacology for June 2024

  • Behnaz Lahooti
  • Inhaled Treprostinil Palmitil in the Sugen/Hypoxia Rat Model
  • Cinnabarinic Acid Protects Against NAFLD
  • CNS Distribution of the ATM Inhibitor AZD1390
  • Effect of Anwulignan on Gastric Injury in Mice
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Latest Fast Forward Articles

  • You have access
    KATP Channel Prodrugs Reduce Inflammatory and Neuropathic Hypersensitivity, Morphine Induced Hypersensitivity, and Precipitated Withdrawal in Mice
    Alexis Doucette, Kayla Johnson, Shelby Hulke, Sunna Mujteba, Elena Miller, Belle Meyer, Peter I Dosa and Amanda H Klein
    Journal of Pharmacology and Experimental Therapeutics March 17, 2023, JPET-AR-2022-001522; DOI: https://doi.org/10.1124/jpet.122.001522
  • You have access
    Metformin Monotherapy Alters the Human Plasma Lipidome Independent of Clinical Markers of Glycemic Control and Cardiovascular Disease Risk in a Type 2 Diabetes Clinical Cohort
    Benjamin Wancewicz, Yanlong Zhu, Rachel J Fenske, Alicia M Weeks, Kent Wenger, Samantha Pabich, Michael Daniels, Margaret Punt, Randall Nall, Darby C Peter, Allan Brasier, Elizabeth D Cox, Dawn Belt Davis, Ying Ge and Michelle Kimple
    Journal of Pharmacology and Experimental Therapeutics March 14, 2023, JPET-AR-2022-001493; DOI: https://doi.org/10.1124/jpet.122.001493
  • You have access
    Assessment of abuse-related discriminative stimulus effects of nicotine aerosol in rodents
    Yasmin Alkhlaif and Keith L. Shelton
    Journal of Pharmacology and Experimental Therapeutics March 14, 2023, JPET-AR-2022-001520; DOI: https://doi.org/10.1124/jpet.122.001520
  • You have access
    In vivo pharmacokinetic and pharmacodynamic properties of the antiarrhythmic molecule ent-verticilide
    Daniel J Blackwell, Abigail N Smith, Tri Q. Do, Aaron Gochman, Jeffrey Schmeckpeper, Corey R. Hopkins, Wendell S Akers, Jeffrey N Johnston and Bjorn Knollmann
    Journal of Pharmacology and Experimental Therapeutics March 9, 2023, JPET-AR-2022-001455; DOI: https://doi.org/10.1124/jpet.122.001455
  • You have access
    Comparison of safety and biological efficacy of anakinra (Kineret ®) dispensed in polycarbonate plastic versus borosilicate glass syringes: a patient-level analysis of VCUART2 and VCUART3 clinical trials
    Azita Talasaz, Robin Sculthorpe, Mary Pak, Michael Lipinski, Charlotte Roberts, Roshanak Markley, Cory Trankle, Justin M Canada, George F Wohlford, Michele Golino, Dave L Dixon, Benjamin Van Tassell and Antonio Abbate
    Journal of Pharmacology and Experimental Therapeutics March 3, 2023, JPET-AR-2022-001404; DOI: https://doi.org/10.1124/jpet.122.001404
  • You have access
    COMBINING SOS1 AND MEK INHIBITORS IN A MURINE MODEL OF PLEXIFORM NEUROFIBROMA RESULTS IN TUMOR SHRINKAGE
    Mark Jackson, Niousha Ahmari, Jianqiang Wu, Tilat A Rizvi, Elizabeth Fugate, Mi-OK Kim, Eva Dombi, Heribert Arnhof, Guido Boehmelt, Matthias J Düchs, Clive J Long, Udo Maier, Francesca Trapani, Marco H. Hofmann and Nancy Ratner
    Journal of Pharmacology and Experimental Therapeutics February 27, 2023, JPET-AR-2022-001431; DOI: https://doi.org/10.1124/jpet.122.001431
View more published ahead of print articles

About Journal of Pharmacology and Experimental Therapeutics

A leading research journal in the field of pharmacology, JPET provides broad coverage of all aspects of the interactions of chemicals with biological systems, including autonomic, behavioral, cardiovascular, cellular, clinical, developmental, gastrointestinal, immuno-, neuro-, pulmonary, and renal pharmacology, as well as analgesics, drug abuse, metabolism and disposition, chemotherapy, and toxicology. 

Current issue

Journal of Pharmacology and Experimental Therapeutics: 385 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 385, Issue 1
1 Apr 2023
  • Table of Contents
  • About the Cover
  • Index by author

JPET is published continuously. Articles are added as they are ready and assigned to monthly issues. Check this site for new content or sign up for content alerts.

TOP 10 REASONS TO SUBMIT TO JPET:

  1. Free ASPET member submission & reduced page charges.
  2. Free color figures.
  3. Free accepted paper PDF access.
  4. Opportunity to Highlight trainee authors.
  5. Showcase important & interesting articles each month.
  6. Timely proofs and listing in PubMed.
  7. Transfer option to any ASPET journal.
  8. A goal to initiate Podcasts for top accepted articles.
  9. A goal of 20 days submission to 1st decision - GOAL MET.
  10. A goal of 9 days from acceptance to publication. - GOAL MET.

EDITOR'S CHOICE ARTICLES FOR MARCH 2023:

  • 3,4-Methylenedioxypyrovalerone High-Responder Phenotype as a Tool to Evaluate Candidate Medications for Stimulant Use Disorder
  • The Effects of Dual GLP-1/Glucagon Receptor Agonists with Different Receptor Selectivity in Mouse Models of Obesity and Nonalcoholic Steatohepatitis
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  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology
  • Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
  • The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
  • A METHOD FOR DETERMINING LOSS OF PAIN SENSATION
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