Supplemental Data
Files in this Data Supplement:
- Supplemental Data -
SUPPLEMENTAL DATA 1. Comparative analysis of the cholesterol-lowering effect of atorvastatin, pravastatin, simvastatin, lovastatin and rosuvastatin in humans with hypercholesterolemia.
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SUPPLEMENTAL DATA 2. Determining ED30 values (i.e. effective dose to reduce plasma TC with 30%) for the different statins in patients with hypercholesterolemia.
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SUPPLEMENTAL DATA 3. Plasma TC levels in E3L mice fed with a HFC diet and after 6-weeks of treatment with different statins at increasing dose.
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SUPPLEMENTAL DATA 4. Plasma TG levels in E3L mice fed with a HFC diet and after 6-weeks of treatment with different statins at increasing dose.
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SUPPLEMENTAL DATA 5. Drug levels of 3H-rosuvastatin, 3H-atorvastatin and 3H-pravastatin in (A) stomach, (B) intestine (tissue plus contents), (C) colon (tissue plus contents) and (D) kidney of E3L mice 30 and 120 minutes after oral dosage (10 mg/kg).