Immune modulatory treatment of trinitrobenzene sulfonic acid colitis with calcitriol is associated with a change of a T helper (Th) 1/Th17 to a Th2 and regulatory T cell …
A number of recent studies testify that calcitriol alone or in combination with corticosteroids
exerts strong immune modulatory activity. As a new approach, we evaluated the …
exerts strong immune modulatory activity. As a new approach, we evaluated the …
Immunomodulatory Effects of 1,25-Dihydroxyvitamin D3 on TH1/TH2 Cytokines in Inflammatory Bowel Disease: An in Vitro Study
S Ardizzone, A Cassinotti, D Trabattoni… - International …, 2009 - journals.sagepub.com
Crohn's disease (CD) is associated with a higher type-1-helper T cell (Th1) cytokine
expression, whereas ulcerative colitis (UC) appears to express a modified Th2 response. In …
expression, whereas ulcerative colitis (UC) appears to express a modified Th2 response. In …
Anti–interleukin 12 treatment regulates apoptosis of Th1 T cells in experimental colitis in mice
IJ Fuss, T Marth, MF Neurath, GR Pearlstein, A Jain… - Gastroenterology, 1999 - Elsevier
Background & Aims: Trinitrobenzene sulfonic acid (TNBS)-induced colitis is a T-helper 1
(Th1) T cell–mediated inflammation that is rapidly reversed by administration of anti …
(Th1) T cell–mediated inflammation that is rapidly reversed by administration of anti …
Efficacy of a potent and safe vitamin D receptor agonist for the treatment of inflammatory bowel disease
Deficiency in 1α, 25-dihydroxyvitamin D3 (1, 25D3) has been suggested as an important
environmental factor for immuno-mediated disorders including inflammatory bowel diseases …
environmental factor for immuno-mediated disorders including inflammatory bowel diseases …
Effects of topical treatment of sodium butyrate and 5-aminosalicylic acid on expression of trefoil factor 3, interleukin 1β, and nuclear factor κB in trinitrobenzene …
M Song, B Xia, J Li - Postgraduate medical journal, 2006 - academic.oup.com
Abstract Background and Aims Butyrate enemas have been shown to be effective in
treatment of ulcerative colitis, but the mechanism of the effects of butyrate is not totally …
treatment of ulcerative colitis, but the mechanism of the effects of butyrate is not totally …
Atorvastatin attenuates TNBS-induced rat colitis: the involvement of the TLR4/NF-kB signaling pathway
A Rashidian, A Muhammadnejad, AR Dehpour… - …, 2016 - Springer
Aim The aim of the present study is to explore whether atorvastatin improves intestinal
inflammation through the inhibition of the TLR4/NFkB signaling pathway in TNBS-induced …
inflammation through the inhibition of the TLR4/NFkB signaling pathway in TNBS-induced …
An oral drug delivery system targeting immune-regulating cells ameliorates mucosal injury in trinitrobenzene sulfonic acid-induced colitis
H Nakase, K Okazaki, Y Tabata, S Uose… - … of Pharmacology and …, 2001 - ASPET
Control of immune-regulating cells in the colonic mucosa is important in the treatment of
patients with inflammatory bowel disease (IBD). The aim of study was to examine the …
patients with inflammatory bowel disease (IBD). The aim of study was to examine the …
Berberine ameliorates chronic relapsing dextran sulfate sodium-induced colitis in C57BL/6 mice by suppressing Th17 responses
Y Li, H Xiao, D Hu, S Fatima, C Lin, H Mu… - Pharmacological …, 2016 - Elsevier
Ulcerative colitis (UC) is an increasingly common condition particularly in developed
countries. The lack of satisfactory treatment has fueled the search for alternative therapeutic …
countries. The lack of satisfactory treatment has fueled the search for alternative therapeutic …
Therapeutic potential of dinitrobenzene sulfonic acid (DNBS)-induced colitis in mice by targeting IL-1β and IL-18
D Impellizzeri, R Siracusa, M Cordaro… - Biochemical …, 2018 - Elsevier
Abstract Interleukin (IL)-1 and IL-18 belong to the IL-1 family of ligands, and their receptors
are members of the IL-1 receptor family. Both cytokines drive an extensive range of pro …
are members of the IL-1 receptor family. Both cytokines drive an extensive range of pro …
Role of T lymphocytes in rat 2, 4, 6-trinitrobenzene sulphonic acid (TNBS) induced colitis: increased mortality after γδ T cell depletion and no effect of αβ T cell …
JC Hoffmann, K Peters, S Henschke, B Herrmann… - Gut, 2001 - gut.bmj.com
BACKGROUND AND AIM Indirect evidence suggests that CD4+ T cells have a pathogenic
while γδ T cells have a protective role in the initiation and perpetuation of inflammatory …
while γδ T cells have a protective role in the initiation and perpetuation of inflammatory …