[PDF][PDF] GABAA receptor trafficking-mediated plasticity of inhibitory synapses
B Luscher, T Fuchs, CL Kilpatrick - Neuron, 2011 - cell.com
Proper developmental, neural cell-type-specific, and activity-dependent regulation of
GABAergic transmission is essential for virtually all aspects of CNS function. The number of …
GABAergic transmission is essential for virtually all aspects of CNS function. The number of …
The role of GABAA receptors in the acute and chronic effects of ethanol: a decade of progress
The past decade has brought many advances in our understanding of GABA A receptor-
mediated ethanol action in the central nervous system. We now know that specific GABA A …
mediated ethanol action in the central nervous system. We now know that specific GABA A …
Regulation of GABAA receptor trafficking, channel activity, and functional plasticity of inhibitory synapses
Neural inhibition in the brain is mainly mediated by ionotropic γ-aminobutyric acid type A
(GABAA) receptors. Different subtypes of these receptors, distinguished by their subunit …
(GABAA) receptors. Different subtypes of these receptors, distinguished by their subunit …
Regulation of GABAARs by phosphorylation
Y Nakamura, LM Darnieder, TZ Deeb… - Advances in pharmacology, 2015 - Elsevier
Abstract γ-Aminobutyric acid type A receptors (GABA A Rs) are the principal mediators of
fast synaptic inhibition in the brain as well as the low persistent extrasynaptic inhibition, both …
fast synaptic inhibition in the brain as well as the low persistent extrasynaptic inhibition, both …
[HTML][HTML] Saracatinib, a Src tyrosine kinase inhibitor, as a disease modifier in the rat DFP model: sex differences, Neurobehavior, gliosis, neurodegeneration, and nitro …
M Gage, M Putra, L Wachter, K Dishman, M Gard… - Antioxidants, 2021 - mdpi.com
Diisopropylfluorophosphate (DFP), an organophosphate nerve agent (OPNA), exposure
causes status epilepticus (SE) and epileptogenesis. In this study, we tested the protective …
causes status epilepticus (SE) and epileptogenesis. In this study, we tested the protective …
Role of the Fyn-PKCδ signaling in SE-induced neuroinflammation and epileptogenesis in experimental models of temporal lobe epilepsy
Status epilepticus (SE) induces neuroinflammation and epileptogenesis, but the
mechanisms are not yet fully delineated. The Fyn, a non-receptor Src family tyrosine kinase …
mechanisms are not yet fully delineated. The Fyn, a non-receptor Src family tyrosine kinase …
Inhibitors of Src family kinases, inducible nitric oxide synthase, and NADPH oxidase as potential CNS drug targets for neurological diseases
MC Gage, T Thippeswamy - CNS drugs, 2021 - Springer
Neurological diseases share common neuroinflammatory and oxidative stress pathways.
Both phenotypic and molecular changes in microglia, astrocytes, and neurons contribute to …
Both phenotypic and molecular changes in microglia, astrocytes, and neurons contribute to …
E-6801, a 5-HT6 receptor agonist, improves recognition memory by combined modulation of cholinergic and glutamatergic neurotransmission in the rat
I Kendall, HA Slotten, X Codony, J Burgueño… - …, 2011 - Springer
Rationale and objectives In rats, 5-hydroxytryptamine 6 (5-HT 6) receptor antagonists
improve learning and memory, but the effects of agonists are poorly defined. This study …
improve learning and memory, but the effects of agonists are poorly defined. This study …
Phosphorylation of GABAA receptors influences receptor trafficking and neurosteroid actions
Rationale Gamma-aminobutyric acid type A receptors (GABA A Rs) are the principal
mediators of inhibitory transmission in the mammalian central nervous system. GABA A Rs …
mediators of inhibitory transmission in the mammalian central nervous system. GABA A Rs …
Enhanced NMDA receptor tyrosine phosphorylation and increased brain injury following neonatal hypoxia–ischemia in mice with neuronal Fyn overexpression
R Knox, C Zhao, D Miguel-Perez, S Wang, J Yuan… - Neurobiology of …, 2013 - Elsevier
The Src family kinases (SFKs) Src and Fyn are implicated in hypoxic–ischemic (HI) injury in
the developing brain. However, it is unclear how these particular SFKs contribute to brain …
the developing brain. However, it is unclear how these particular SFKs contribute to brain …