Neurobiology of cocaine abuse

WL Woolverton, KM Johnson - Trends in pharmacological sciences, 1992 - cell.com
… Bill Woolverton and Ken Johnson stress that continued collaboration between behavioral
pharmacologists and neuroscientists is critical for a complete understanding of the effects of …

Biochemical and histological evidence that methylenedioxymethylamphetamine (MDMA) is toxic to neurons in the rat brain.

…, G Vosmer, RM Virus, WL Woolverton… - … of Pharmacology and …, 1987 - ASPET
(+/-)-3,4-Methylenedioxymethylamphetamine (MDMA) was administered sc to rats (10, 20 or
40 mg/kg b. wt.) and guinea pigs (20 mg/kg) twice a day for 4 days, 2 weeks before …

Effects of increasing the magnitude of an alternative reinforcer on drug choice in a discrete-trials choice procedure

MA Nader, WL Woolverton - Psychopharmacology, 1991 - Springer
… The results of the present experiment confirm previous findings (Woolverton and Balster
1981) that in monkeys allowed to choose between cocaine and food in a discrete-trials choice …

Relationship between the serotonergic activity and reinforcing effects of a series of amphetamine analogs

…, RB Rothman, BE Blough, WL Woolverton - … of Pharmacology and …, 2005 - ASPET
… In preliminary experiments (WL Woolverton, unpublished data), the addition of histamine to
an injection of cocaine can act to punish cocaine self-administration. Considering the clinical …

Long-term effects of chronic methamphetamine administration in rhesus monkeys

WL Woolverton, GA Ricaurte, LS Forno, LS Seiden - Brain research, 1989 - Elsevier
Biochemical and neuropathological effects of exposure to a high dose regimen of
methamphetamine were evaluated in rhesus monkeys approximately 4 years after the last drug …

Effects of environmental conditions on the psychological well-being of primates: A review of the literature

WL Woolverton, NA Ator, PM Beardsley, ME Carroll - Life sciences, 1989 - Elsevier
Amendments made to the Animal Welfare Act in 1985 require primate researchers to provide
“a physical environment adequate to promote the psychological well-being of primates”. …

Elevated level of metabotropic glutamate receptor 2/3 in the prefrontal cortex in major depression

AM Feyissa, WL Woolverton, JJ Miguel-Hidalgo… - Progress in Neuro …, 2010 - Elsevier
Clinical, postmortem and preclinical research strongly implicates dysregulation of
glutamatergic neurotransmission in major depressive disorder (MDD). Recently, metabotropic …

Intravenous self-administration of dopamine receptor agonists by rhesus monkeys.

WL Woolverton, LI Goldberg, JZ Ginos - Journal of Pharmacology and …, 1984 - ASPET
Pharmacological studies have provided important information relevant to the behavioral
role of central nervous system (CNS) dopamine (DA) as well as the existence of multiple DA …

Effects of clomipramine on self-control choice in Lewis and Fischer 344 rats

KG Anderson, WL Woolverton - Pharmacology Biochemistry and Behavior, 2005 - Elsevier
Rates of delay discounting (impulsive choice) have been shown to vary among individuals,
particularly people who abuse drugs relative to those who do not, but factors that may …

[HTML][HTML] Mechanistic role for a novel glucocorticoid-KLF11 (TIEG2) protein pathway in stress-induced monoamine oxidase A expression

…, MC Austin, J Wang, IA Paul, WL Woolverton… - Journal of Biological …, 2012 - ASBMB
Chronic stress is a risk factor for psychiatric illnesses, including depressive disorders, and is
characterized by increased blood glucocorticoids and brain monoamine oxidase A (MAO A, …