Differential regulation of dopamine receptors after chronic typical and atypical antipsychotic drug treatment

FI Tarazi, WJ Florijn, I Creese - Neuroscience, 1997 - Elsevier
Changes in dopamine receptor subtype binding in different brain regions were examined
after 28 days treatment of rats with haloperidol, raclopride, clozapine or SCH23390 using in …

Optimizing anesthetic regimen for surgery in mice through minimization of hemodynamic, metabolic, and inflammatory perturbations

…, SM Houten, MW Hollmann, WJ Florijn - Experimental …, 2014 - journals.sagepub.com
The role of anesthetics in animal research models is crucial, yet often ignored, and is almost
never the primary focus of examination. Here, we investigated the impact of anesthetic …

Dopamine receptor subtypes: differential regulation after 8 months treatment with antipsychotic drugs

WJ Florijn, FI Tarazi, I Creese - Journal of Pharmacology and Experimental …, 1997 - ASPET
Regulation of dopamine receptor subtypes was determined after long-term (8 mo) administration
of typical and atypical antipsychotic drugs using 3 H-nemonapride, 3 H-raclopride, 3 H-…

Regulation of ionotropic glutamate receptors following subchronic and chronic treatment with typical and atypical antipsychotics

FI Tarazi, WJ Florijn, I Creese - Psychopharmacology, 1996 - Springer
Quantitative in vitro receptor autoradiography was used to examine changes in three
ionotropic glutamate receptor subtypes using 3 H-MK801 (NMDA-R antagonist), 3 H-CNQX (AMPA-…

Peptide-induced grooming behavior and caudate nucleus dopamine release

WJ Florijn, AJGD Holtmaat, H de Lang, H Spierenburg… - Brain research, 1993 - Elsevier
We simultaneously measured the display of grooming behavior and, by monitoring the
extracellular dopamine concentration via transversal microdialysis, the release of dopamine in …

Phorbol 12, 13-dibutyrate enhances electrically stimulated neuromessenger release from rat dorsal hippocampal slices in vitro

DHG Versteeg, WJ Florijn - Life sciences, 1987 - Elsevier
The protein kinase C activator 4β-phorbol 12, 13-dibutyrate (PDB) enhanced the electrically
stimulated release of radiolabelled noradrenaline (NA), acetylcholine (ACh) and 5-…

ACTH/MSH-like peptides inhibit the binding of dopaminergic ligands to the dopamine D2 receptor in vitro

WJ Florijn, T De Boer, JADM Tonnaer… - European Journal of …, 1991 - Elsevier
ACTH-(1-24) decreased the binding of the dopamine D 2 receptor agonist, [ 3 H]N-propylnorapomorphine
([ 3 H]NPA), to rat striatal membranes in a concentration-dependent manner, …

Adrenocorticotropin/α‐melanocyte‐stimulating hormone (ACTH/MSH)‐like peptides modulate adenylate cyclase activity in rat brain slices: evidence for an ACTH/MSH …

WJ Florijn, AH Mulder, DHG Versteeg… - Journal of …, 1993 - Wiley Online Library
The regulation of adenylate cyclase activity by adrenocorticotropin/α‐melanocyte–stimulating
hormone (ACTH/MSH)‐like peptides was investigated in rat brain slices using a …

Synchronism of pressor response and grooming behavior in freely moving, conscious rats following intracerebroventicular administration of ACTH/MSH-like peptides

DHG Versteeg, WJ Florijn, AJGD Holtmaat, WH Gispen… - Brain research, 1993 - Elsevier
… ACTH-(7-16)-NH 2, which has been found by Florijn et alJ to be an even more potent
displacer of radiolabelled ligands from their membrane receptors in vitro than ACTH-(1-24), has …

Identification of HASH2-positive extravillus trophoblast cells in the peripheral blood of pregnant women

…, JMG van Vugt, AAM Könst, MAM Mulders, WJ Florijn… - Placenta, 1998 - Elsevier
In order to develop a non-invasive procedure for prenatal diagnosis of genetic diseases, a
procedure was established which permits isolation and detection of trophoblast cells …