ADAM17 upregulation in human renal disease: a role in modulating TGF-α availability?

WB Melenhorst, L Visser, A Timmer… - American Journal …, 2009 - journals.physiology.org
A disintegrin and metalloproteinase (ADAM)17 sheds growth factors from the cell membrane,
including epidermal growth factor receptor (EGFR) ligand transforming growth factor (TGF)-…

Nerve decompression surgery as treatment for peripheral diabetic neuropathy: literature overview and awareness among medical professionals

WB Melenhorst, ML Overgoor, EG Gonera… - Annals of plastic …, 2009 - journals.lww.com
Peripheral diabetic neuropathy (PDN) is one of the major complications arising in patients
with diabetes. Since PDN is traditionally considered an irreversible disorder, treatment has …

Tissue stromal vascular fraction improves early scar healing: a prospective randomized multicenter clinical trial

…, KM Vermeulen, WB Melenhorst… - Aesthetic surgery …, 2022 - academic.oup.com
Background Wound healing and scar formation depends on a plethora of factors. Given the
impact of abnormal scar formation, interventions aimed to improve scar formation would be …

Irreversible electroporation for colorectal liver metastases

HJ Scheffer, MCAM Melenhorst, AM Echenique… - Techniques in vascular …, 2015 - Elsevier
Image-guided tumor ablation techniques have significantly broadened the treatment possibilities
for primary and secondary hepatic malignancies. A new ablation technique, irreversible …

Challenges and opportunities of CAR T-cell therapies for CLL

…, C Grégoire, B Oliveira, K Chung, JJ Melenhorst - Seminars in …, 2023 - Elsevier
… In addition, Dr Melenhorst has a patent to Methods for improving the efficacy and expansion
of immune cells issued, a patent to Biomarkers predictive of therapeutic responsiveness to …

Response to: Thoughts on Tissue Stromal Vascular Fraction for Early Scar Healing

…, KM Vermeulen, WB Melenhorst… - Aesthetic Surgery …, 2022 - academic.oup.com
We would like to thank Sun and Zhao for their response and comments 1 on our randomized
clinical trial studying the effect of tissue-stromal vascular fraction (tSVF) on early scar …

Activity of mesothelin-specific chimeric antigen receptor T cells against pancreatic carcinoma metastases in a phase 1 trial

…, AM Nelson, WL Gladney, BL Levine, JJ Melenhorst… - Gastroenterology, 2018 - Elsevier
… Joseph Melenhorst are inventors of intellectual property related to chimeric antigen receptor
T cells that is licensed by the University of Pennsylvania to Novartis. The remaining authors …

[CITATION][C] Medical students need more education on hygiene behavior

WB Melenhorst, HP Poos… - American journal of …, 2009 - ajicjournal.org
To the Editor: A worldwide pandemic of H1N1 influenza virus infection, popularly known as
swine flu, has affected several thousand people to date. In view of infection control and …

Response assessment after (chemo) radiotherapy for rectal cancer: why are we missing complete responses with MRI and endoscopy?

…, BJP Hupkens, SO Breukink, J Melenhorst… - European Journal of …, 2019 - Elsevier
Purpose To evaluate what features on restaging MRI and endoscopy led to a false clinical
diagnosis of residual tumour in patients with a pathological complete response after rectal …

Is watch and wait a safe and effective way to treat rectal cancer in older patients?

…, RGH Beets-Tan, GL Beets, J Melenhorst… - European Journal of …, 2020 - Elsevier
Introduction The aim was assess the oncological and functional outcome of the watch-and-wait
(W&W) approach in older patients with a clinical (near)complete response after …