The novel melatonin agonist agomelatine (S20098) is an antagonist at 5-hydroxytryptamine2C receptors, blockade of which enhances the activity of frontocortical …

…, A Dekeyne, A Newman-Tancredi, V Pasteau… - … of Pharmacology and …, 2003 - ASPET
Agomelatine (S20098) displayed pK i values of 6.4 and 6.2 at native (porcine) and cloned,
human (h)5-hydroxytryptamine (5-HT) 2C receptors, respectively. It also interacted with h5-HT …

An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells

…, N Daigle, OV Zatsepina, F Pasteau… - The Journal of cell …, 2001 - rupress.org
The nuclear pore complexes (NPCs) are evolutionarily conserved assemblies that allow
traffic between the cytoplasm and the nucleus. In this study, we have identified and …

A visual servoing approach for autonomous corridor following and doorway passing in a wheelchair

F Pasteau, VK Narayanan, M Babel… - Robotics and Autonomous …, 2016 - Elsevier
Navigating within an unknown indoor environment using an electric wheelchair is a challenging
task, especially if the user suffers from severe disabilities. In order to reduce fatigability …

Human dopamine D3 receptors mediate mitogen-activated protein kinase activation via a phosphatidylinositol 3-kinase and an atypical protein kinase C-dependent …

D Cussac, A Newman-Tancredi, V Pasteau… - Molecular …, 1999 - ASPET
The mitogen-activated protein kinase (MAPK) cascade is stimulated by both receptor tyrosine
kinases and G protein-coupled receptors. We show that recombinant human dopamine D …

Differential activation of Gq/11 and Gi3 proteins at 5-hydroxytryptamine2C receptors revealed by antibody capture assays: influence of receptor reserve and …

…, A Newman-Tancredi, D Duqueyroix, V Pasteau… - Molecular …, 2002 - ASPET
As determined by a guanosine 5′-O-(3-[ 35 S]thio)triphosphate ([ 35 S]GTPγS) binding assay,
which does not distinguish G protein subtypes, 5-hydroxytryptamine (5-HT) and 2(S)- 1-(6…

Signaling pathways leading to phosphorylation of Akt and GSK-3β by activation of cloned human and rat cerebral D2 and D3 receptors

CM la Cour, MJ Salles, V Pasteau, MJ Millan - Molecular pharmacology, 2011 - ASPET
Although dopamine (DA) regulates the serine/threonine kinase Akt and its downstream
substrate glycogen synthase kinase-3β (GSK-3β), the direct influence of dopaminergic receptors …

Functional characterization of a Nup159p-containing nuclear pore subcomplex

N Belgareh, C Snay-Hodge, F Pasteau… - Molecular biology of …, 1998 - Am Soc Cell Biol
Nup159p/Rat7p is an essential FG repeat–containing nucleoporin localized at the cytoplasmic
face of the nuclear pore complex (NPC) and involved in poly(A) + RNA export and NPC …

G protein activation by human dopamine D3 receptors in high-expressing Chinese hamster ovary cells: a guanosine-5′-O-(3-[35S] thio)-triphosphate binding and …

…, D Cussac, V Audinot, V Pasteau… - Molecular …, 1999 - ASPET
Despite extensive study, the G protein coupling of dopamine D 3 receptors is poorly
understood. In this study, we used guanosine-5′-O-(3-[ 35 S]thio)-triphosphate ([ 35 S]-GTPγS) …

Design of an immersive simulator for assisted power wheelchair driving

…, F Nouviale, VK Narayanan, F Pasteau… - 2017 International …, 2017 - ieeexplore.ieee.org
Driving a power wheelchair is a difficult and complex visual-cognitive task. As a result, some
people with visual and/or cognitive disabilities cannot access the benefits of a power …

The radium treatment of cancer of the prostate

O Pasteau, Degrais - Archives of the Roentgen Ray, 1914 - birpublications.org
WE have already published our views on the surgical treatment of Cancer of the Prostate. 1
We return to it for two reasons: one," that the matter formed one of the subjects of discussion …