Histone deacetylase inhibitor enhances recovery after AKI

…, C Woods, J West, VN Korotchenko… - Journal of the …, 2013 - journals.lww.com
At present, there are no effective therapies to ameliorate injury, accelerate recovery, or
prevent postinjury fibrosis after AKI. Here, we sought to identify candidate compounds that …

In vivo structure–activity relationship studies support allosteric targeting of a dual specificity phosphatase

VN Korotchenko, M Saydmohammed… - …, 2014 - Wiley Online Library
Dual specificity phosphatase 6 (DUSP6) functions as a feedback attenuator of fibroblast
growth factor signaling during development. In vitro high throughput chemical screening …

Olefination of carbonyl compounds: modern and classical methods

VN Korotchenko, VG Nenajdenko… - Russian chemical …, 2004 - pubs.rsc.org
The published data on the methods for alkene synthesis by olefination of carbonyl compounds
are generalised and systematised. The main attention is given to the use of transition …

A novel synthetic approach to dichlorostyrenes

AV Shastin, VN Korotchenko, VG Nenajdenko… - Tetrahedron, 2000 - Elsevier
We found that N-unsubstituted hydrazones of aromatic aldehydes can be easily converted
to the corresponding 1,1-dichlorostyrenes in the reaction with carbon tetrachloride using …

A novel approach to fluoro-containing alkenes

VN Korotchenko, AV Shastin, VG Nenajdenko… - Tetrahedron, 2001 - Elsevier
A new and general one-pot transformation of aromatic aldehydes to fluorinated olefins
containing –CHC(Cl)CF 3 or –CHC(F)CClF 2 moieties is described. Freons CCl 3 CF 3 and …

A novel direct synthesis of (2, 2-difluorovinyl) benzenes from aromatic aldehydes

VG Nenajdenko, GN Varseev, VN Korotchenko… - Journal of fluorine …, 2003 - Elsevier
A novel catalytic approach to (2,2-difluorovinyl)benzenes has been developed. It was found
that hydrazones of aromatic aldehydes generated in situ could be converted to the …

A tumor cell-selective inhibitor of mitogen-activated protein kinase phosphatases sensitizes breast cancer cells to lymphokine-activated killer cell activity

…, LA Vernetti, L Caprio, K Davis, VN Korotchenko… - … of Pharmacology and …, 2017 - ASPET
Dual specificity mitogen-activated protein kinase (MAPK) phosphatases [dual specificity
phosphatase/MAP kinase phosphatase (DUSP-MKP)] have been hypothesized to maintain …

Olefination of aromatic ketones: synthesis of mono-and dihaloalkenes

VN Korotchenko, AV Shastin, VG Nenajdenko… - Journal of the …, 2002 - pubs.rsc.org
… Bull., 1999, 48, 2184 Search PubMed ; (b) AV Shastin, VN Korotchenko, VG Nenajdenko
and ES Balenkova, Tetrahedron, 2000, 56, 6557 CrossRef … Bull., 2001, 50, 1401 Search …

Novel efficient synthesis of dibromoalkenes. A first example of catalytic olefination of aliphatic carbonyl compounds

VN Korotchenko, AV Shastin, VG Nenajdenko… - Organic & …, 2003 - pubs.rsc.org
A new simple and efficient one pot transformation of various aliphatic carbonyl compounds to
the corresponding dibromoalkenes is described. A wide range of hydrazones of aldehydes …

Reaction of CBrF2–CBrF2 with hydrazones of aromatic aldehydes: Novel efficient synthesis of fluorocontaining alkanes, alkenes and alkynes

VG Nenajdenko, GN Varseev, VN Korotchenko… - Journal of fluorine …, 2004 - Elsevier
An olefination of hydrazones of aromatic aldehydes by CBrF 2 –CBrF 2 under copper
catalysis was investigated. In situ prepared aldehydes hydrazones were converted to (3-bromo-2,2,…