Prostaglandin E2 receptors in bone formation
M Li, DD Thompson, VM Paralkar - International orthopaedics, 2007 - Springer
Prostaglandins, PGE 2 in particular, have diverse actions on various organs, including
inflammation, bone healing, bone formation, embryo implantation, induction of labour and …
inflammation, bone healing, bone formation, embryo implantation, induction of labour and …
Transforming growth factor β type 1 binds to collagen IV of basement membrane matrix: Implications for development
VM Paralkar, S Vukicevic, AH Reddi - Developmental biology, 1991 - Elsevier
The interaction of transforming growth factor β (TGF β) with extracellular matrix macromolecules
was examined by using radiolabeled TGF β and various matrix macromolecules …
was examined by using radiolabeled TGF β and various matrix macromolecules …
[HTML][HTML] Cloning and characterization of a novel member of the transforming growth factor-β/bone morphogenetic protein family
VM Paralkar, AL Vail, WA Grasser, TA Brown… - Journal of Biological …, 1998 - ASBMB
Members of the transforming growth factor-β (TGF-β) superfamily of growth and differentiation
factors have been identified in a wide variety of organisms, ranging from invertebrates to …
factors have been identified in a wide variety of organisms, ranging from invertebrates to …
Deletion of the P2X7 Nucleotide Receptor Reveals Its Regulatory Roles in Bone Formation and Resorption
…, DT Crawford, WA Grasser, VM Paralkar… - Molecular …, 2003 - academic.oup.com
The P2X 7 nucleotide receptor is an ATP-gated ion channel expressed widely in cells of
hematopoietic origin. Our purpose was to explore the involvement of the P2X 7 receptor in bone …
hematopoietic origin. Our purpose was to explore the involvement of the P2X 7 receptor in bone …
An EP2 receptor-selective prostaglandin E2 agonist induces bone healing
VM Paralkar, F Borovecki, HZ Ke… - Proceedings of the …, 2003 - National Acad Sciences
The morbidity and mortality associated with impaired/delayed fracture healing remain high.
Our objective was to identify a small nonpeptidyl molecule with the ability to promote fracture …
Our objective was to identify a small nonpeptidyl molecule with the ability to promote fracture …
Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1
…, MF Hamou, DW Fairlie, SN Breit, VM Paralkar… - Oncogene, 2002 - nature.com
Human astrocytic brain tumors select for mutations in the p53 tumor suppressor gene early
in malignant progression. p53 is activated upon various kinds of cellular stress leading to …
in malignant progression. p53 is activated upon various kinds of cellular stress leading to …
Proline-rich tyrosine kinase 2 regulates osteoprogenitor cells and bone formation, and offers an anabolic treatment approach for osteoporosis
…, DF Gebhard, VM Paralkar… - Proceedings of the …, 2007 - National Acad Sciences
Bone is accrued and maintained primarily through the coupled actions of bone-forming
osteoblasts and bone-resorbing osteoclasts. Cumulative in vitro studies indicated that proline-…
osteoblasts and bone-resorbing osteoclasts. Cumulative in vitro studies indicated that proline-…
[HTML][HTML] Interaction of osteogenin, a heparin binding bone morphogenetic protein, with type IV collagen.
VM Paralkar, AK Nandedkar, RH Pointer… - Journal of Biological …, 1990 - Elsevier
Osteogenin, an extracellular matrix component of bone, is a heparin binding differentiation
factor that initiates endochondral bone formation in rats when implanted subcutaneously with …
factor that initiates endochondral bone formation in rats when implanted subcutaneously with …
A Novel, Non‐Prostanoid EP2 Receptor‐Selective Prostaglandin E2 Agonist Stimulates Local Bone Formation and Enhances Fracture Healing
…, Y Li, DT Crawford, VM Paralkar… - Journal of Bone and …, 2003 - academic.oup.com
CP‐533,536, a newly discovered, non‐prostanoid EP2 receptor‐selective PGE 2 agonist,
stimulates local bone formation and enhances fracture healing in rat models. Introduction: …
stimulates local bone formation and enhances fracture healing in rat models. Introduction: …
Recombinant human bone morphogenetic protein 2B stimulates PC12 cell differentiation: potentiation and binding to type IV collagen.
VM Paralkar, BS Weeks, YM Yu, HK Kleinman… - The Journal of cell …, 1992 - rupress.org
… Recombinant BMP 2B was iodinated by the chloramine T method as described previously
(Paralkar et al., 1991a). For Scatchard analysis, PC12 ceils were washed three times with …
(Paralkar et al., 1991a). For Scatchard analysis, PC12 ceils were washed three times with …