Gonadotropin-inhibitory hormone (GnIH) and its control of central and peripheral reproductive function
Identification of novel neurohormones that regulate the reproductive axis is essential for the
progress of neuroendocrinology. The decapeptide gonadotropin-releasing hormone (GnRH) …
progress of neuroendocrinology. The decapeptide gonadotropin-releasing hormone (GnRH) …
Discovery and evolutionary history of gonadotrophin‐inhibitory hormone and kisspeptin: new key neuropeptides controlling reproduction
…, GE Bentley, LJ Kriegsfeld, T Osugi… - Journal of …, 2010 - Wiley Online Library
Gonadotrophin‐releasing hormone (GnRH) is the primary hypothalamic factor responsible
for the control of gonadotrophin secretion in vertebrates. However, within the last decade, two …
for the control of gonadotrophin secretion in vertebrates. However, within the last decade, two …
The general and comparative biology of gonadotropin-inhibitory hormone (GnIH)
…, GE Bentley, T Ubuka, E Saigoh, H Yin, T Osugi… - General and …, 2007 - Elsevier
The decapeptide gonadotropin-releasing hormone (GnRH) is the primary factor responsible
for the hypothalamic control of gonadotropin secretion. Gonadal sex steroids and inhibin …
for the hypothalamic control of gonadotropin secretion. Gonadal sex steroids and inhibin …
Biphasic role for Wnt/β-catenin signaling in cardiac specification in zebrafish and embryonic stem cells
S Ueno, G Weidinger, T Osugi… - Proceedings of the …, 2007 - National Acad Sciences
Understanding pathways controlling cardiac development may offer insights that are useful
for stem cell-based cardiac repair. Developmental studies indicate that the Wnt/β-catenin …
for stem cell-based cardiac repair. Developmental studies indicate that the Wnt/β-catenin …
Signal transducer and activator of transcription 3 in the heart transduces not only a hypertrophic signal but a protective signal against doxorubicin-induced …
…, E Tone, M Funamoto, T Osugi… - Proceedings of the …, 2000 - National Acad Sciences
The signal transducer and activator of transcription (STAT) 3, a transcriptional factor downstream
of several cytokines, is activated by Janus kinase families and plays a pivotal role in …
of several cytokines, is activated by Janus kinase families and plays a pivotal role in …
Hypophysiotropic role of RFamide-related peptide-3 in the inhibition of LH secretion in female rats
…, T Iwasa, T Yasui, M Irahara, T Osugi… - Journal of …, 2008 - joe.bioscientifica.com
Gonadotropin-inhibitory hormone (GnIH), a newly discovered hypothalamic RFamide peptide,
inhibits reproductive activity by decreasing gonadotropin synthesis and release in birds. …
inhibits reproductive activity by decreasing gonadotropin synthesis and release in birds. …
[HTML][HTML] Endogenous Wnt/β-catenin signaling is required for cardiac differentiation in human embryonic stem cells
SL Paige, T Osugi, OK Afanasiev, L Pabon… - PloS one, 2010 - journals.plos.org
Background Wnt/β-catenin signaling is an important regulator of differentiation and morphogenesis
that can also control stem cell fates. Our group has developed an efficient protocol to …
that can also control stem cell fates. Our group has developed an efficient protocol to …
Gonadotropin-inhibitory hormone neurons interact directly with gonadotropin-releasing hormone-I and-II neurons in European starling brain
…, S Kim, Y Huang, J Reid, J Jiang, T Osugi… - …, 2008 - academic.oup.com
… of 1:1000 in 0.4% PBS-T. Three subsequent washes in 0.2% PBS-T were followed by
incubation for 1 h in biotinylated goat antirabbit IgG (1:1000 in 0.2% PBS-T). Sections were then …
incubation for 1 h in biotinylated goat antirabbit IgG (1:1000 in 0.2% PBS-T). Sections were then …
[HTML][HTML] Identification of human GnIH homologs, RFRP-1 and RFRP-3, and the cognate receptor, GPR147 in the human hypothalamic pituitary axis
… the sections in 2% normal goat serum in PBS-T, sections were incubated overnight at 4C in
the white-crowned sparrow GnIH antibody in PBS-T at a concentration of 1∶5000. The next …
the white-crowned sparrow GnIH antibody in PBS-T at a concentration of 1∶5000. The next …
Activation of signal transducer and activator of transcription 3 protects cardiomyocytes from hypoxia/reoxygenation-induced oxidative stress through the upregulation …
…, Y Fujio, M Funamoto, MI Darville, DL Eizirik, T Osugi… - Circulation, 2001 - Am Heart Assoc
Background Mice with cardiac-specific overexpression of signal transducer and activator of
transcription 3 (STAT3) are resistant to doxorubicin-induced damage. The STAT3 signal may …
transcription 3 (STAT3) are resistant to doxorubicin-induced damage. The STAT3 signal may …