Role of oxidative stress in cardiovascular diseases

NS Dhalla, RM Temsah, T Netticadan - Journal of hypertension, 2000 - journals.lww.com
Objectives In view of the critical role of intracellular Ca 2+-overload in the genesis of myocyte
dysfunction and the ability of reactive oxygen species (ROS) to induce the intracellular Ca 2…

[HTML][HTML] Dietary flaxseed as a strategy for improving human health

…, TG Maddaford, JA Austria, M Aliani, T Netticadan… - Nutrients, 2019 - mdpi.com
Flaxseed is a rich source of the omega-3 fatty acid, alpha linolenic acid, the lignan
secoisolariciresinol diglucoside and fiber. These compounds provide bioactivity of value to the health …

[HTML][HTML] Grape bioactive molecules, and the potential health benefits in reducing the risk of heart diseases

A Sabra, T Netticadan, C Wijekoon - Food Chemistry: X, 2021 - Elsevier
Grapes are a rich source of bioactive molecules including phenolic acids, flavonoids,
anthocyanins, stilbenes, and lipids. These are the compounds which contribute to the health …

[HTML][HTML] Antihyperglycemic effects of short term resveratrol supplementation in type 2 diabetic patients

…, SJ Rekabpour, T Netticadan - Evidence-Based …, 2013 - hindawi.com
… Thomas Netticadan and Ali Movahed originated the idea for this human trial. Ali Movahed,
Xavier Lieben Louis, Sijo Joseph Thandapilly, Liping Yu, and Thomas Netticadan were …

Resveratrol prevents the development of pathological cardiac hypertrophy and contractile dysfunction in the SHR without lowering blood pressure

…, MA Kopilas, HD Anderson, T Netticadan - American journal of …, 2010 - academic.oup.com
Background Cardiac hypertrophy is a compensatory enlargement of the heart in response to
stress such as hypertension. It is beneficial in reducing stress placed on the heart. However, …

[HTML][HTML] Flaxseed: Its bioactive components and their cardiovascular benefits

M Parikh, T Netticadan… - American Journal of …, 2018 - journals.physiology.org
Cardiovascular disease remains the leading cause of mortality and morbidity worldwide. The
inclusion of functional foods and natural health products in the diet are gaining increasing …

Potential of resveratrol in the treatment of heart failure

…, SJ Thandapilly, A Movahed, S Zieroth, T Netticadan - Life sciences, 2014 - Elsevier
The concept of food has expanded beyond its traditional role of survival and hunger satisfaction,
to include a role in the prevention and treatment of disease. Polyphenols are classes of …

Alterations in sarcoplasmic reticulum function and gene expression in ischemic-reperfused rat heart

RM Temsah, T Netticadan… - American Journal …, 1999 - journals.physiology.org
In view of the critical role of sarcoplasmic reticular (SR) Ca 2+ release and the Ca 2+ pump
in cardiac contraction-relaxation, this study was undertaken to assess the status of SR …

Prevention of concentric hypertrophy and diastolic impairment in aortic-banded rats treated with resveratrol

…, DK Das, T Netticadan - American Journal of …, 2007 - journals.physiology.org
This study was designed to examine the effects of the antioxidant resveratrol on cardiac
structure and function in pressure overload (PO)-induced cardiac hypertrophy. Male Sprague-…

Resveratrol protects adult cardiomyocytes against oxidative stress mediated cell injury

…, L Yu, SJ Thandapilly, XL Louis, T Netticadan - Archives of biochemistry …, 2012 - Elsevier
Recent studies from our laboratory have showed that resveratrol, a polyphenol found
predominantly in grapes rendered strong cardioprotection in animal models of heart disease. The …