Prevention of T Cell Anergy by Signaling Through the γc Chain of the IL-2 Receptor

VA Boussiotis, DL Barber, T Nakarai, GJ Freeman… - Science, 1994 - science.org
When stimulated through their antigen receptor without requisite costimulation, T cells enter
a state of antigen-specific unresponsiveness, termed anergy. In this study, signaling through …

[HTML][HTML] Effect of gasoline pool fire on liquid hydrogen storage tank in hybrid hydrogen–gasoline fueling station

…, J Nakayama, T Nakarai, N Kasai, T Shibutani… - international journal of …, 2016 - Elsevier
… 5 shows the relations between the maximum temperature T max on the hydrogen tank and
the exposure time t at different distances for the emissivity values ε = 0.7 and ε = 0.2. As D …

Interleukin 2 receptor gamma chain expression on resting and activated lymphoid cells.

T Nakarai, MJ Robertson, M Streuli, Z Wu… - The Journal of …, 1994 - rupress.org
… cell surface expression by immunofluorescence, resting T cells were found to express
low … , T cells expressed higher levels of oe,/~, and 3'. However, at later time points, T cells …

Regulatory dysfunction of the interleukin-2 receptor during HIV infection and the impact of triple combination therapy

…, JL Moreau, MP Treilhou, T Nakarai… - Proceedings of the …, 1998 - National Acad Sciences
… the main regulatory determinant of T cell reactivity. Although it … , CD8 T lymphocytes,
and monocytes, but not on CD4 T … Moreover, cells involved in cellular immunity and CD4 T

Malignant clonal expansion of large granular lymphocytes with a Leu-11+, Leu-7-surface phenotype: in vitro responsiveness of malignant cells to recombinant human …

…, M Taniguchi, A Matsuda, K Taga, T Nakarai… - 1986 - ashpublications.org
… These LGLs were E rosette+ and Fc(IgG) receptor+ and therefore are referred to as T
The LGLs showed no rearrangement of T cell receptor C beta genes. The natural killer (NK) …

Further analysis of interleukin-2 receptor subunit expression on the different human peripheral blood mononuclear cell subsets

…, K Sun, O Salvucci, T Nakarai… - Blood, The Journal …, 1998 - ashpublications.org
… detectable on CD4 T lymphocytes. No expression of the IL-2R chains is found for the B
lymphocytes. In most donors, the three chains are not detectable on CD8 T lymphocytes, but for a …

Expression of the IL-2 receptor gamma subunit in resting human CD4 T lymphocytes: mRNA is constitutively transcribed and the protein stored as an intracellular …

…, D David, JL Moreau, A Cayota, T Nakarai… - International …, 1997 - academic.oup.com
… have been studied after activation of CD4 T lymphocytes and compared with induction of IL-…
T cell activation and induction of the IL-2Rα and IL-2Rβ genes. We hypothesize that in CD4 T

Transcript synthesis and surface expression of the interleukin-2 receptor (alpha-, beta-, and gamma-chain) by normal and malignant myeloid cells

RR Schumann, T Nakarai, HJ Gruss, MA Brach… - 1996 - ashpublications.org
… HOUGH HUMAN interleukin-2 (IL-2) plays a central role in growth and function of T
lymphocytes, it also boosts the activity of other lymphoid cells such as B lymphoctes, natural killer …

[PDF][PDF] Pharmacological profile of FK480, a novel cholecystokinin type-A receptor antagonist: comparison to loxiglumide.

H Ito, H Sogabe, T Nakarai, Y Sato, M Tomoi… - … of Pharmacology and …, 1994 - Citeseer
Materials and Methods Receptor binding studies. I-CCK-8 binding assays for rat pan-creas,
guinea-pig gallbladder and guinea-pig cerebral cortex were similar to those described by …

Effects of calcium antagonists on anti-cancer drug toxicity to haematopoietic progenitor cells in normal human bone marrow

T Nakarai, S Koizumi - Leukemia research, 1990 - Elsevier
… Student's t-test was used for statistical analysis. … & Matsumoto T. (1985) Potentiation of
vincristine effect in human and murine gliomas by calcium channel blockers or calmodulin …