Close association between clearance of recombinant human granulocyte colony-stimulating factor (G-CSF) and G-CSF receptor on neutrophils in cancer patients

K Terashi, M Oka, S Ohdo, T Furukubo… - Antimicrobial agents …, 1999 - Am Soc Microbiol
… Serum G-CSF concentrations and the percentage of G-CSF receptor-positive neutrophils on
the days of neutropenia and neutrophilia were compared by the paired t test. The number of …

Influence of serum in hemodialysis patients on the expression of intestinal and hepatic transporters for the excretion of pravastatin

…, T Furukubo, S Izumi, T Yamakawa… - Therapeutic …, 2012 - Wiley Online Library
… (C T ) number at which the amplification reaches a significant threshold. The C T values were
… (15), and ΔC T was calculated by subtracting the C T of the control gene (β2 m) from the C …

Polarization of impurity emission lines from a tokamak plasma

…, T Kallstenius, M Goto, H Kawase, T Furukubo… - Physical Review E, 1996 - APS
… The WT-3 tokamak at Kyoto University had the major and minor radii of 0.65 and 0.21 m,
respectively, and the toroidal magnetic field was 1.5 T at the poloidal center. A plasma was …

Three-dimensional band mapping of graphite

…, H Daimon, H Totsuka, K Ogawa, T Furukubo… - Applied physics …, 2002 - pubs.aip.org
We developed a method to visualize the curved surfaces of valence band dispersion by a
display-type spherical mirror analyzer. The π and σ band “surfaces” of graphite measured and …

Cooperative inhibitory effects of uremic toxins and other serum components on OATP1B1-mediated transport of SN-38

…, T Furukubo, S Izumi, T Yamakawa, T Minegaki… - Cancer chemotherapy …, 2017 - Springer
… Statistical significance of differences between two groups was determined using unpaired
Student’s t test and for three or more independent groups using one-way ANOVA followed by …

[HTML][HTML] Effects of decreased vitamin D and accumulated uremic toxin on human CYP3A4 activity in patients with end-stage renal disease

…, T Furukubo, S Izumi, T Yamakawa, T Minegaki… - Toxins, 2013 - mdpi.com
In patients with end-stage renal disease, not only renal clearance but also hepatic clearance
is known to be impaired. For instance, the concentration of erythromycin, a substrate of …

Inhibitory effects of uraemic toxins 3-indoxyl sulfate and p-cresol on losartan metabolism in vitro

…, T Furukubo, S Izumi, T Yamakawa… - Journal of Pharmacy …, 2010 - academic.oup.com
Objectives The purpose of this study was to clarify the cause of decreased metabolic
clearance of losartan in patients with end-stage renal failure. The influence of serum from …

Involvement of histone hyperacetylation in triggering DNA fragmentation of rat thymocytes undergoing apoptosis

E Lee, T Furukubo, T Miyabe, A Yamauchi, K Kariya - FEBS letters, 1996 - Elsevier
The treatment of rat thymocytes with trichostatin A and sodium butyrate, which are inhibitors
of histone deacetylase, resulted in an increase in DNA fragmentation in a concentration-…

Interactions between clarithromycin and digoxin in patients with end-stage renal disease.

S Hirata, S Izumi, T Furukubo, M Ota… - … Journal of Clinical …, 2005 - search.ebscohost.com
Objective: To report a significant in crease in the serum levels of digoxin associated with the
use of Clarithromycin in six patients under going renal replacement therapy. Case summary: …

Possibility of decrease in CYP1A2 function in patients with end‐stage renal disease

…, T Furukubo, S Izumi, T Yamakawa… - Therapeutic …, 2014 - Wiley Online Library
Propranolol, the substrate of cytochrome P450 ( CYP ) 1A2 and CYP2D6 , has been reported
to be in high concentrations in end‐stage renal disease ( ESRD ) patients. This has been …