Massive CA1/2 neuronal loss with intraneuronal and N-terminal truncated Aβ42 accumulation in a novel Alzheimer transgenic model

…, V Vingtdeux, E Van De Steeg, G Ret, T Canton… - The American journal of …, 2004 - Elsevier
Alzheimer's disease (AD) is characterized by a substantial degeneration of pyramidal neurons
and the appearance of neuritic plaques and neurofibrillary tangles. Here we present a …

Time sequence of maturation of dystrophic neurites associated with Aβ deposits in APP/PS1 transgenic mice

…, N Touchet, B Bonici, M Planche, T Canton… - Experimental …, 2003 - Elsevier
Several novel transgenic mouse models expressing different mutant APPs in combination
with mutant PS1 have been developed. These models have been analyzed to investigate the …

Inhibition by riluzole of electrophysiological responses mediated by rat kainate and NMDA receptors expressed in Xenopus oocytes

MW Debono, J Le Guern, T Canton, A Doble… - European journal of …, 1993 - Elsevier
The effects of riluzole, an anticonvulsant and neuroprotective compound, on excitatory amino
acid-evoked currents were studied in Xenopus laevis oocytes injected with mRNA from rat …

Ascitic fluid polymorphonuclear cell count and serum to ascites albumin gradient in the diagnosis of bacterial peritonitis

A Albillos, V Cuervas-Mons, I Millan, T Canton… - Gastroenterology, 1990 - Elsevier
The analysis of ascitic fluid has been complicated by several recently reported new tests. To
simplify this assessment, we evaluated nine parameters prospectively and simultaneously …

[HTML][HTML] Sex differences in IL-17 contribute to chronicity in male versus female urinary tract infection

AZ Scharff, M Rousseau, LL Mariano, T Canton… - JCI insight, 2019 - ncbi.nlm.nih.gov
… To have a global view of UPEC-infected cells, we overlaid traditionally gated populations
on a t-distributed stochastic neighbor embedding (tSNE) plot of concatenated infected bladder …

Designing a template bank to observe compact binary coalescences in Advanced LIGO's second observing run

TD Canton, IW Harry - arXiv preprint arXiv:1705.01845, 2017 - arxiv.org
We describe the methodology and novel techniques used to construct a set of waveforms,
or template bank, applicable to searches for compact binary coalescences in Advanced …

RPR 119990, a novel α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid antagonist: synthesis, pharmacological properties, and activity in an animal model of …

T Canton, GA Böhme, A Boireau, F Bordier… - … of Pharmacology and …, 2001 - ASPET
α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptor antagonists
are of potential interest for the treatment of certain acute and chronic neurodegenerative …

An adrenaline-induced vasospasm as the form of presentation of variant angina

RC JA, OD JF, T Cantón, R Barciela… - Revista Española de …, 1999 - europepmc.org
A 41-year-old-man without previous ischemic heart disease, developed a severe anaphylactic
reaction. After administration of epinephrine (0.5 mg) the patient complained of chest pain…

The mechanism of action of zopiclone

A Doble, T Canton, C Malgouris, JM Stutzmann… - European …, 1995 - cambridge.org
Canton T, Doble A. Evidence for different binding domaines on the GABA&enzodiazepine
… Correlation between gamma-aminobutyric acid(A&receptor ligand-induce$changes in t-…

A summary of multimessenger science with neutron star mergers

E Burns, A Tohuvavohu, J Buckley, TD Canton… - arXiv preprint arXiv …, 2019 - arxiv.org
Neutron star mergers, referring to both binary neutron star and neutron star black hole
mergers, are the canonical multimessenger events. They have been detected across the …