[% ID/g]) at 5 mmand increasedslightlyto 0.26% lD/g at 60 mm. The tumor uptake exhibiteda
maximumat 60 mm (1.72% ID/g), resultingin a tumor-to-brainratio increaseof 5.58 at 5 mmto …

Organoboranes have proven to be versatile intermediates in a number of synthetic
sequences. The utility of the borane reagents is centered on the stereodefined nature of their …

18 F-T807 is a PET radiotracer developed for imaging tau protein aggregates, which are
implicated in neurologic disorders including Alzheimer disease and traumatic brain injury (TBI). …

Fluorine‐18 labeled 7‐(6‐fluoropyridin‐3‐yl)‐5H‐pyrido[4,3‐b]indole ([ 18 F]T807) is a
potent and selective agent for imaging paired helical filaments of tau and is among the most …

Interfering with the assembly of Amyloid β (Aβ) peptides from monomer to oligomeric
species and fibrils or promoting their clearance from the brain are targets of anti-Aβ-directed …

Sodium perborate, a readily available and inexpensive reagent, efficiently oxidizes
organoboranes. The reagent permits the oxidation of a wide variety of functionally substituted …

Optimal delivery of immunologically active cells to target tissue(s) is important for improving
adoptive immunotherapy of neoplastic diseases. By using positron emission tomography, we …

Zinc, copper, and iron ions are involved in amyloid-beta (Aβ) deposition and stabilization in
Alzheimer’s disease (AD). Consequently, metal binding agents that prevent metal-Aβ …

… Shoup … Shoup has no conflict of interest. He is listed on the patent as an inventor and
does not own any shares or options in FluoroPharma. Dr. … Shoup …

In@ the biodistaibutionof biotin2 indIcatedmorebinding to normal musde withan infectionto
normal musde ratioof0. 58 ±0.07. This lack of selectivity illustrates the importance of the side…