… Gram negative clinical isolates were not involved in this study as it is commonly known that
Staphylococcus aureus is gram positive. Clinical isolates were gram positive, which may be …

… This study was undertaken to investigate both the mechanism(s) of its anticancer activity …
predominates in postmitotic cardiomyocytes, and pixantrone is demonstrated in this study to be …

… Currently, it is reported that the defective NF-κB activation is responsible for the suppressive
phenotype of TAM ( 13 , 21 ). However, there is no report on the TLR-mediated p38 and …

A series of arylnaphthalene lignan lactones based on the structure of the phyllanthusmins, a
class of potent natural products possessing diphyllin as the aglycone, has been synthesized …

Staphylococcus aureus is the most frequently isolated pathogen causing bloodstream infections,
skin and soft tissue infections and pneumonia. Lymphocyte is an important immune cell…

DNA topoisomerase IIα (TOP2α) is a prominent target for anticancer drugs whose clinical
efficacy is often limited by chemoresistance. Using antibody specific for the N-terminal of TOP2α…

… Of note, the MTX results were consistent with the literature as MTX is also a known DNA
intercalator. This is presumably its mechanism of MPG inhibition, which was unsuitable for our …

… Because NO is a biologic messenger molecule and has been reported to induce synthesis
of anticancer proteins5 and IFN- is a wellknown anticancer cytokine,6 we investigated the …

Obesity is considered as an independent risk factor for breast cancer (BCa) and plays a major
role in the breast tumor microenvironment. The etiology and mechanisms by which obesity …

The objective of this study was to develop chitosan-based delivery of cobalt oxide
nanoparticles to human leukemic cells and investigate their specific induction of apoptosis. The …