Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily

…, B Burchell, C Guillemette, S Ikushiro… - Pharmacogenetics …, 2005 - journals.lww.com
Several novel UDP glycosyltransferase (UGT) genes, mainly UDP glucuronosyltransferases,
have been identified in the human, mouse and rat genomes and in other mammalian …

[HTML][HTML] Biochemical and molecular aspects of genetic disorders of bilirubin metabolism

T Iyanagi, Y Emi, S Ikushiro - … et Biophysica Acta (BBA)-Molecular Basis of …, 1998 - Elsevier
… Gilbert’s syndrome have an unconjugated serum bilirubin level of 60 μM or below. Gilbert’s
The molecular bases of CN syndrome and Gilbert’s syndrome have recently been …

Quantitative analysis of UDP-glucuronosyltransferase (UGT) 1A and UGT2B expression levels in human livers

…, T Fukami, M Takamiya, Y Aoki, S Ikushiro… - Drug Metabolism and …, 2009 - ASPET
… After an initial denaturation at 95C for 30 s, amplification was performed by denaturation at
94C for 4 s, annealing at an appropriate temperature for 7 s, and extension at 72C for 20 s for …

Glucuronidation of the environmental oestrogen bisphenol A by an isoform of UDP-glucuronosyltransferase, UGT2B1, in the rat liver

…, T Kobayashi, H Inoue, S IKUSHIRO… - Biochemical …, 1999 - portlandpress.com
… the presence of other isoform(s) responsible for glucuronidating BPA in the liver of female
rats. … The relative mobilities of the 18 S and 28 S ribosomal RNA species are shown as size …

[HTML][HTML] Mammalian Cytochrome P450-Dependent Metabolism of Polychlorinated Dibenzo-p-dioxins and Coplanar Polychlorinated Biphenyls

H Inui, T Itoh, K Yamamoto, SI Ikushiro… - International journal of …, 2014 - mdpi.com
… Although the S. cerevisiae genome contains three … genes have successfully been expressed
in S. cerevisiae [26,27]. … is that whole cells of recombinant S. cereviasiae producing human …

Crystal Structure of CYP105A1 (P450SU-1) in Complex with 1α,25-Dihydroxyvitamin D3,

…, S Yoneda, M Yamada, M Kamakura, S Ikushiro… - Biochemistry, 2008 - ACS Publications
S. griseolus CYP105A1 and ferredoxin genes were kindly provided by Sumitomo Chemical
… enzymes play a role in xenobiotic metabolism in S. griseolus. Because none of the three Arg …

The configuration of the 17-hydroxy group variably influences the glucuronidation of β-estradiol and epiestradiol by human UDP-glucuronosyltransferases

K Itäaho, PI Mackenzie, S Ikushiro, JO Miners… - Drug Metabolism and …, 2008 - ASPET
… × S/(K m + S), where v is the initial velocity of the reaction, S is … inhibition equation [v = V max
× S/(K s + S + S 2 /K i ), where … Hill equation [v = V max × S n /(K A n + S n ), where K A is the …

Expression of hepatic UDP-glucuronosyltransferase 1A1 and 1A6 correlated with increased expression of the nuclear constitutive androstane receptor and …

M Osabe, J Sugatani, T Fukuyama, S Ikushiro… - Drug metabolism and …, 2008 - ASPET
… The thermal cycle conditions were as follows: incubate for 10 s at 95C, followed by two-step
polymerase chain reaction for 40 cycles of 95C for 5 s followed by 60C for 30 s. β-Actin was …

A possible mechanism for decrease in serum thyroxine level by polychlorinated biphenyls in Wistar and Gunn rats

Y Kato, S Ikushiro, K Haraguchi… - Toxicological …, 2004 - academic.oup.com
We have previously demonstrated that in mice, the decrease in serum thyroxine (T 4 ) level
by polychlorinated biphenyls (PCBs) occurs without an increase in the UDP-…

Protein− Protein Interactions between UDP-Glucuronosyltransferase Isozymes in Rat Hepatic Microsomes

S Ikushiro, Y Emi, T Iyanagi - Biochemistry, 1997 - ACS Publications
… The immunostaining and silver staining patterns of the fractions containing 50 kDa protein(s)
(fractions 51−57) are shown in panels 1 and 2 of Figure 1B, respectively. The silver-stained …