… RW Grady assisted PJ Giardina and gave important scientific advice. EJ Neufeld assisted
in care of patients in Boston and did some studies. R Séchaud was co-author of the protocol …

Progressive iron overload is the most salient and ultimately fatal complication of β-thalassemia.
However, little is known about the relationship among ineffective erythropoiesis (IE), the …

Osteoporosis is a frequent problem in disorders characterized by iron overload, such as the
thalassemias and hereditary hemochromatosis. The exact role of iron in the development of …

Adults with β thalassemia major frequently have low BMD, fractures, and bone pain. The
purpose of this study was to determine the prevalence of low BMD, fractures, and bone pain in …

Excessive iron absorption is one of the main features of β-thalassemia and can lead to
severe morbidity and mortality. Serial analyses of β-thalassemic mice indicate that while …

Regulation of erythropoiesis is achieved by the integration of distinct signals. Among them,
macrophages are emerging as erythropoietin-complementary regulators of erythroid …

Purpose : The surgical correction of bladder exstrophy to achieve continence with voiding
remains a challenging problem for the urologist. Since 1989 we have performed complete …

CoQ links the sn-glycerol-3-phosphate dehydrogenase and oxidase components of the
cyanide-insensitive, non-cytochrome-mediated respiratory system of bloodstream African …

Two-dimensional (2D) semiconducting transition metal dichalcogenides could be used to
build high-performance flexible electronics. However, flexible field-effect transistors (FETs) …

This study aimed to determine differences in the rates of growth, endocrine‐ and calcium‐related
abnormalities in the various thalassemia syndromes in North America treated with …