Effects of glucagon-like peptide-1 in patients with acute myocardial infarction and left ventricular dysfunction after successful reperfusion

…, GG Sokos, G Miske, A Shah, D Elahi, RP Shannon - Circulation, 2004 - Am Heart Assoc
Background— Glucose-insulin-potassium infusions are beneficial in uncomplicated patients
with acute myocardial infarction (AMI) but are of unproven efficacy in AMI with left ventricular …

Assessment of cardiac dysfunction in a randomized trial comparing doxorubicin and cyclophosphamide followed by paclitaxel, with or without trastuzumab as adjuvant …

…, M Ewer, D Keefe, RP Shannon… - Journal of Clinical …, 2005 - ascopubs.org
Purpose Trastuzumab is effective in treating human epidermal growth factor receptor 2 (HER2)
–positive breast cancer, but it increases frequency of cardiac dysfunction (CD) when …

Glucagon-like peptide-1 infusion improves left ventricular ejection fraction and functional status in patients with chronic heart failure

…, LA Nikolaidis, S Mankad, D Elahi, RP Shannon - Journal of cardiac …, 2006 - Elsevier
BACKGROUND: Insulin resistance is present in the setting of congestive heart failure.
Glucagon-like peptide-1 (GLP-1) is a naturally occurring incretin with both insulinotropic and …

Diabetic cardiomyopathy: the search for a unifying hypothesis

IG Poornima, P Parikh, RP Shannon - Circulation research, 2006 - Am Heart Assoc
Although diabetes is recognized as a potent and prevalent risk factor for ischemic heart disease,
less is known as to whether diabetes causes an altered cardiac phenotype independent …

Potential effects of aggressive decongestion during the treatment of decompensated heart failure on renal function and survival

…, J Chen, BD McCauley, SE Kimmel, RP Shannon - Circulation, 2010 - Am Heart Assoc
Background— Overly aggressive diuresis leading to intravascular volume depletion has been
proposed as a cause for worsening renal function during the treatment of decompensated …

Recombinant glucagon-like peptide-1 increases myocardial glucose uptake and improves left ventricular performance in conscious dogs with pacing-induced dilated …

…, L Zourelias, C Stolarski, Y Shen, RP Shannon - Circulation, 2004 - Am Heart Assoc
Background— The failing heart demonstrates a preference for glucose as its metabolic
substrate. Whether enhancing myocardial glucose uptake favorably influences left ventricular (LV…

Direct effects of glucagon-like peptide-1 on myocardial contractility and glucose uptake in normal and postischemic isolated rat hearts

…, H Bolukoglu, I Poornima, YT Shen, RP Shannon - … of Pharmacology and …, 2006 - ASPET
Recent evidence suggests that glucagon-like peptide-1 (GLP-1) enhances recovery of left
ventricular (LV) function after transient coronary artery occlusion. However, it is uncertain …

Active metabolite of GLP-1 mediates myocardial glucose uptake and improves left ventricular performance in conscious dogs with dilated cardiomyopathy

…, D Elahi, YT Shen, RP Shannon - American Journal of …, 2005 - journals.physiology.org
We have shown previously that the glucagon-like peptide-1 (GLP-1)-(7–36) amide increases
myocardial glucose uptake and improves left ventricular (LV) and systemic hemodynamics …

Effect of glucagon-like peptide-1 (GLP-1) on glycemic control and left ventricular function in patients undergoing coronary artery bypass grafting

…, G Marrone, DH Benckart, D Elahi, RP Shannon - The American journal of …, 2007 - Elsevier
Increasing evidence suggests that tight glycemic control improves clinical outcomes after
coronary artery bypass grafting (CABG). However, the risk for hypoglycemia with insulin often …

Patient-centered community health worker intervention to improve posthospital outcomes: a randomized clinical trial

…, S McCollum, J Sellman, RP Shannon… - JAMA internal …, 2014 - jamanetwork.com
Importance Socioeconomic and behavioral factors can negatively influence posthospital
outcomes among patients of low socioeconomic status (SES). Traditional hospital personnel …