[HTML][HTML] Telmisartan for treatment of Covid-19 patients: An open multicenter randomized clinical trial

…, MC Rubio, S Sarquis, F Wahlmann, RP Rothlin - …, 2021 - thelancet.com
Background Angiotensin receptor blockers (ARBs), such as telmisartan, have been
postulated to treat Covid-19-induced lung inflammation. Methods This is a parallel-group, …

Telmisartan as tentative angiotensin receptor blocker therapeutic for COVID‐19

RP Rothlin, HM Vetulli, M Duarte… - Drug development …, 2020 - Wiley Online Library
In late 2019, a new coronavirus emerged in Wuhan Province, China, causing lung complications
similar to those produced by the SARS coronavirus in the 2002–2003 epidemic. This …

[HTML][HTML] Angiotensin receptor blockers for COVID-19: pathophysiological and pharmacological considerations about ongoing and future prospective clinical trials

RP Rothlin, M Duarte, FG Pelorosso… - Frontiers in …, 2021 - frontiersin.org
COVID-19 pandemic demands a swift response to find therapeutic tools that effectively
reduce morbidity and mortality. Despite initial fears, evidence from retrospective observational …

Role of the α-adrenoceptor in regulating noradrenaline overflow by nerve stimulation

MA Enero, SZ Langer, RP Rothlin… - British journal of …, 1972 - ncbi.nlm.nih.gov
A study of the actions of phenoxybenzamine on transmitter overflow, neuronal and
extraneuronal uptake of noradrenaline and in causing α-adrenoceptor blockade was carried …

[HTML][HTML] Telmisartan and losartan: The marked differences between their chemical and pharmacological properties may explain the difference in therapeutic efficacy in …

RP Rothlin, FG Pelorosso, M Duarte… - Pharmacology …, 2023 - ncbi.nlm.nih.gov
At the beginning of the COVID-19 pandemic, Gurwitz, 1 taking into account that SARS-CoV-2
virus enters cells after binding to ACE2 (Angiotensin Converting Enzyme 2), proposed the …

Telmisartan for treatment of Covid-19 patients: an open randomized clinical trial. Preliminary report

…, MC Rubio, S Sarquis, F Wahlmann, RP Rothlin - MedRxiv, 2020 - medrxiv.org
… Pharmacological analysis made by Rothlin et al. has postulated that telmisartan may be
the best candidate to study. Therefore, the objective of this study was to assess whether …

[HTML][HTML] Characterization of α1-adrenoceptor subtypes mediating vasoconstriction in human umbilical vein

…, RM Torres, SP Sardi, RP Rothlin - British journal of …, 1999 - ncbi.nlm.nih.gov
… Andrea Emilse Errasti, 1 María Pía Rogines Velo, 1 Rodrigo Martín Torres, 1 Sergio
Pablo Sardi, 1 and Rodolfo Pedro Rothlin 1, * … ELGOYHEN AB, LORENZO PS, ROTHLIN …

Bradykinin B1 receptors in human umbilical vein

SP Sardi, H Pérez, P Antúnez, RP Rothlin - European journal of …, 1997 - Elsevier
The present study was undertaken to demonstrate the presence of bradykinin B 1 receptors
mediating contraction of human umbilical vein. The bradykinin B 1 receptor selective agonist…

Pathophysiology and therapeutic possibilities of calcitonin gene-related peptide in hypertension.

I Márquez-Rodas, F Longo, RP Rothlin… - Journal of physiology …, 2006 - europepmc.org
Calcitonin gene related peptide (CGRP), a 37 amino acid neuropeptide, is the most potent
vasodilator known. Participation of CGRP in hypertension and related diseases, such as …

[HTML][HTML] Pharmacological characterization of muscarinic receptor subtypes mediating vasoconstriction of human umbilical vein

…, MG Verdi, MC Rodriguez, RP Rothlin - British journal of …, 2006 - ncbi.nlm.nih.gov
… DARAY FM, MINVIELLE AI, PUPPO S., ROTHLIN RP Pharmacological characterization
of prostanoid receptors mediating vasoconstriction in human umbilical vein. Br. J …