A lymphotoxin-β-specific receptor
PD Crowe, TL VanArsdale, BN Walter, CF Ware… - Science, 1994 - science.org
Tumor necrosis factor (TNF) and lymphotoxin-α (LT-α) are members of a family of secreted
and cell surface cytokines that participate in the regulation of immune and inflammatory …
and cell surface cytokines that participate in the regulation of immune and inflammatory …
[HTML][HTML] A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin
DG Alleva, PD Crowe, L Jin, WW Kwok… - The Journal of …, 2001 - Am Soc Clin Investig
The 9–23 amino acid region of the insulin B chain (B (9-23) ) is a dominant epitope recognized
by pathogenic T lymphocytes in nonobese diabetic mice, the animal model for type 1 …
by pathogenic T lymphocytes in nonobese diabetic mice, the animal model for type 1 …
The ligands and receptors of the lymphotoxin system
CF Ware, TL VanArsdale, PD Crowe, JL Browning - Pathways for cytolysis, 1995 - Springer
The tumor necrosis factor (TNF)-related cytokines have emerged over the past 2 years as a
large family of pleiotropic mediators of host defense and immune regulation. Members of this …
large family of pleiotropic mediators of host defense and immune regulation. Members of this …
Expression of surface lymphotoxin and tumor necrosis factor on activated T, B, and natural killer cells.
CF Ware, PD Crowe, MH Grayson… - … (Baltimore, Md.: 1950 …, 1992 - journals.aai.org
The expression of membrane-associated forms of lymphotoxin (LT) and TNF were examined
on cell lines of T, B, and myeloid origin, IL-2 dependent T cell clones, and peripheral blood …
on cell lines of T, B, and myeloid origin, IL-2 dependent T cell clones, and peripheral blood …
Tumor necrosis factor (TNF) receptor expression in T lymphocytes. Differential regulation of the type I TNF receptor during activation of resting and effector T cells.
CF Ware, PD Crowe, TL Vanarsdale… - … (Baltimore, Md.: 1950 …, 1991 - journals.aai.org
The expression of TNF-alpha receptors (TNFR) was examined on a CD4+ T cell hybridoma,
transformed T cell lines, CTL clones, and activated T cells from peripheral blood to …
transformed T cell lines, CTL clones, and activated T cells from peripheral blood to …
CRF receptor type 1 and 2 expression and anatomical distribution in the rat colon
E Chatzaki, PD Crowe, L Wang, M Million… - Journal of …, 2004 - Wiley Online Library
Corticotropin‐releasing factor (CRF) receptor agonists administered peripherally increase
colonic propulsive motility and fecal output in experimental animals. In addition, endogenous …
colonic propulsive motility and fecal output in experimental animals. In addition, endogenous …
A metalloprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes.
PD Crowe, BN Walter, KM Mohler… - The Journal of …, 1995 - rupress.org
TNF is synthesized as a 26-kD membrane-anchored precursor and is proteolytically
processed at the cell surface to yield the mature secreted 17-kD polypeptide. The 80-kD tumor …
processed at the cell surface to yield the mature secreted 17-kD polypeptide. The 80-kD tumor …
Regulation of murine macrophage proinflammatory and anti-inflammatory cytokines by ligands for peroxisome proliferator-activated receptor-γ: counter-regulatory …
…, SA Boehme, PJ Conlon, PD Crowe - Journal of leukocyte …, 2002 - academic.oup.com
… Paul D Crowe Paul D Crowe … David G Alleva, Eric B Johnson, Francisco M Lio, Stefen A
Boehme, Paul J Conlon, Paul D Crowe, Regulation of murine macrophage proinflammatory and …
Boehme, Paul J Conlon, Paul D Crowe, Regulation of murine macrophage proinflammatory and …
Immunological characterization and therapeutic activity of an altered-peptide ligand, NBI-6024, based on the immunodominant type 1 diabetes autoantigen insulin B …
…, EB Johnson, T Motheral, A Putnam, PD Crowe… - Diabetes, 2002 - Am Diabetes Assoc
The nonobese diabetic (NOD) mouse is a good model for human type 1 diabetes, which is
characterized by autoreactive T-cell-mediated destruction of insulin-producing islet β-cells of …
characterized by autoreactive T-cell-mediated destruction of insulin-producing islet β-cells of …
A novel water-soluble selective CRF1 receptor antagonist, NBI 35965, blunts stress-induced visceral hyperalgesia and colonic motor function in rats
M Million, DE Grigoriadis, S Sullivan, PD Crowe… - Brain research, 2003 - Elsevier
The stress response involves the activation of two corticotropin-releasing factor (CRF) receptor
subtypes. We investigated the role of CRF 1 in stress-related visceral responses. A novel …
subtypes. We investigated the role of CRF 1 in stress-related visceral responses. A novel …