Curcumin, the yellow pigment in turmeric, prevents malignancies in the intestinal tract of
rodents. It is under clinical evaluation as a potential colon cancer chemopreventive agent. The …

Curcumin, a constituent of the spice turmeric, has been shown to reduce the adenoma
burden in rodent models of colorectal cancer accompanied by a reduction of levels of the …

Studies in vitro and in animal models of colorectal and hepatocellular cancers suggest that
curcumin is an effective chemopreventive agent. In this pilot trial, we investigated whether …

This review provides a framework contributing to the risk assessment of acrylamide in food.
It is based on the outcome of the ILSI Europe FOSIE process, a risk assessment framework …

Resveratrol is a cancer preventative agent that is found in red wine. Piceatannol is a closely
related stilbene that has antileukaemic activity and is also a tyrosine kinase inhibitor. …

Advances in laboratory techniques have led to a rapidly increasing use of biomarkers in
epidemiological studies. Biomarkers of internal dose, early biological change, susceptibility and …

Resveratrol (trans-3, 5, 4′-trihydroxystilbene) is a naturally occurring polyphenol with cancer
chemopreventive properties in preclinical models of carcinogenesis, including those of …

Over the past 40 years considerable emphasis has been placed on the development of accurate
and sensitive methods for the detection and quantitation of DNA adducts. The formation …

Indole-3-carbinol (I3C) and 3,3′-diindolylmethane (DIM) are promising cancer chemopreventive
agents in rodent models, but there is a paucity of data on their pharmacokinetics and …

Exposure to high levels of environmental air pollution is known to be associated with an
increased carcinogenic risk. The individual contribution to this risk derived from specific …