The investigation of heritable susceptibility to disease is an effort to associate disease
phenotype with underlying genotype. Such genotype:phenotype associations have been …

… Address for reprint requests and other correspondence: PA Doris, Brown Foundation Inst. of
… Kainer DB, Doris PA. Cyclophilin B expression in renal proximal tubules of hypertensive rats…

Objective To determine plasma levels of the endogenous bufodienolide Na+/K+ ATPase
inhibitor, marinobufagenin-like factor (MBG), in normotensive pregnancy and in preeclampsia, …

The highly conserved cardiotonic steroid (CS) binding site present on the ubiquitous membrane
sodium pump, sodium, potassium-ATPase, appears to have been conserved by no force …

Background— Modulation of endogenous epoxide levels by soluble epoxide hydrolase (sEH)
in the endothelium represents an important mechanism in the regulation of cardiovascular …

Single nucleotide polymorphisms (SNPs) are currently being identified and mapped at a
remarkable pace, providing a rich genetic resource with vast potential for disease gene …

The aim of the study was to further investigate the nature of endogenous digitalis-like factors
stimulated by acute plasma volume expansion (VE), 10 male Fisher 344XNB rats were …

Background— We studied the growth-promoting effects of 2 sodium pump–selective cardiotonic
steroids, ouabain and marinobufagenin, on cultured cells from vascular smooth muscle (…

Stroke is the leading cause of severe disability and the third leading cause of death, accounting
for one of every 15 deaths in the USA. We investigated the association of polymorphisms …

An increasing body of evidence suggests that an endogenous mammalian bufadienolide (BD)
may be involved in the regulation of Na + ,K + -ATPase activity and the pathogenesis of …