In heart failure, the renin-angiotensin-aldosterone and the sympathetic systems are
overactivated and lead to formation of cardiac fibrosis, which contributes to the aggravation of …

Anti-hypertensive agents may differently stimulate compensatory neuro-hormonal
mechanisms and induce different effects on the cardiovascular remodeling and function. The …

The purpose of the present study was to determine whether the administration of an antagonist
of aldosterone could prevent the fibrosis induced by an acute injection of isoprenaline. …

The strategy of diuretic drug administration remains to be defined in heart failure as experimental
and clinical evidence have clearly established the benefit of neurohormonal blockade. …

… gauche retrouvait une artérite granulomateuse avec épaississement non inflammatoire
de l’intima, une destruction de la limitante élastique interne, sans atteinte de la média ni de l’…

… O objetivo desta pesquisa foi avaliar e comparar a Reserva Tocaia e Estação Ecológica,
quanto à riqueza, abundância, diversidade e uniformidade da macrofauna próximos aos …

… Por fim, quanto a renda mensal, a DAP mais elevada foi entre aqueles com o menor valor
de ganho (R$ 500,00), com o valor médio de R$ 32,25. Verificouse também que o nível de …

The current study was designed to determine whether castration with or without testosterone
replacement resulted in changes in cardiac sympathetic nerve activity in rats with heart …

Hydrochlorothiazide is a common diuretic antihypertensive drug of the thiazide family. Its
poor aqueous solubility is one of the reasons for its limited bioavailability after oral …

OBJECTIVE: To find a more excellent large-dose isoproterenol (ISO) induced heart failure (HF)
rat model. METHODS: 166 male Wistar rats were divided into four groups, normal group (…