AIM: To investigate if an immune imbalance may account for the development and progression
of chronic radiation enteritis. We analyzed the Th1/Th2 immune response profile early …

Radiation-induced intestinal injuries, including inflammation and immune response, remain
a limiting factor in the effectiveness of pelvic radiotherapy and in the patient's quality of life …

Diethylenetriaminepentaacetic acid (DTPA) is currently still the only known chelating drug
that can be used for decorporation of internalized plutonium (Pu) and americium (Am). It is …

After inhalation of plutonium oxides containing various percentages of americium in rats, we
identified an acellular transient pulmonary compartment, the epithelial lining fluid (ELF), in …

In this study, we assessed the efficacy of unilamellar 110-nm liposomes encapsulating the
chelating agent diethylenetriaminepentaacetic acid (DTPA) in plutonium-exposed rats. Rats …

Purpose: As part of the European project ‘CBRN crisis management: Architecture, Technologies
and Operational Procedures’ (CATO), an open Toolbox is in development that will …

The aim of this study is to propose a single modeling structure to describe both plutonium
and americium decorporation by DTPA, which is based on hypotheses mostly validated by …

… Both parts were tightly sealed by a lubricated Teflon O-ring secured by removable metal …
and held in place in the chamber ports by soft Teflon O-rings. Rats were restrained inside these …

… Endogenous peroxidase activity was quenched with blocking solution (3 g/LH 2 O 2 in
methanol). Sections were exposed to the TUNEL reaction mixture at 37C for 1 h. After washing in …

Drosophila translational elongation factor-1γ (EF1γ) interacts in the yeast two-hybrid system
with DOA, the LAMMER protein kinase of Drosophila. Analysis of mutant EF1γ alleles …