Assessment of 18F-PI-2620 as a biomarker in progressive supranuclear palsy

…, A Schildan, M Patt, B Neumaier, O Barret… - JAMA …, 2020 - jamanetwork.com
… Dr Barret reported other support from Piramal during the conduct of the study. Dr Russell
reported other from InviCRO during the conduct of the study. Dr Stephens reported personal …

Measurement of the proton structure function F2 at very low Q2 at HERA

…, KC Voss, A Weber, H Wieber, DS Bailey, O Barret… - Physics Letters B, 2000 - Elsevier
A measurement of the proton structure function F 2 (x,Q 2 ) is presented in the kinematic range
0.045 GeV 2 <Q 2 <0.65 GeV 2 and 6·10 −7 <x<1·10 −3 . The results were obtained using …

Tau PET imaging with 18F-PI-2620 in patients with Alzheimer disease and healthy controls: a first-in-humans study

A Mueller, S Bullich, O Barret, J Madonia… - Journal of Nuclear …, 2020 - Soc Nuclear Med
18 F-PI-2620 is a PET tracer with high binding affinity for aggregated tau, a key pathologic
feature of Alzheimer disease (AD) and other neurodegenerative disorders. Preclinically, 18 F-…

Increased microglial activation in patients with Parkinson disease using [18F]-DPA714 TSPO PET imaging

…, B Kuhnast, MA Peyronneau, O Barret… - Parkinsonism & related …, 2021 - Elsevier
Introduction Increasing evidence suggests that neuroinflammation is active in Parkinson
disease (PD) and contributes to neurodegeneration. This process can be studied in vivo with …

Intrastriatal alpha-synuclein fibrils in monkeys: spreading, imaging and neuropathological changes

Y Chu, S Muller, A Tavares, O Barret, D Alagille… - Brain, 2019 - academic.oup.com
… The immunohistochemical reaction was completed with 0.05% DAB and 0.005% H 2 O 2 .
Sections were mounted on gelatin-coated slides, dehydrated through graded alcohol, cleared …

[18F]GTP1 (Genentech Tau Probe 1), a radioligand for detecting neurofibrillary tangle tau pathology in Alzheimer's disease

…, A Ogasawara, JN Tinianow, HS Gill, O Barret… - European journal of …, 2019 - Springer
Objective Neurofibrillary tangles (NFTs), consisting of intracellular aggregates of the tau
protein, are a pathological hallmark of Alzheimer’s disease (AD). Here we report the …

[HTML][HTML] Brain microglia activation and peripheral adaptive immunity in Parkinson's disease: a multimodal PET study

…, TB Song, XL Liu, YX Yao, CS Zhao, O Barret… - Journal of …, 2022 - Springer
Background Abnormal activation of immune system is an important pathogenesis of
Parkinson’s disease, but the relationship between peripheral inflammation, central microglia …

How affected is oxygen metabolism in DWI lesions? A combined acute stroke PET-MR study

…, TD Fryer, S Harding, CJ Price, HA Green, O Barret… - Neurology, 2006 - AAN Enterprises
O (2 × 5-minute frames at the end of the administration), followed by a 20-minute steady-state
inhalation of 7,200 MBq of 15 O … -s inhalation of 300 MBq of C 15 O (single 5-minute frame) …

The phosphodiesterase 10 positron emission tomography tracer,[18F] MNI-659, as a novel biomarker for early Huntington disease

DS Russell, O Barret, DL Jennings, JH Friedman… - JAMA …, 2014 - jamanetwork.com
Importance In Huntington disease (HD) striatal neuron loss precedes and predicts motor
signs or symptoms. Current imaging biomarkers lack adequate sensitivity for assessing the …

An adaptive filter for suppression of cardiac and respiratory noise in MRI time series data

RHR Deckers, P van Gelderen, M Ries, O Barret… - Neuroimage, 2006 - Elsevier
The quality of MRI time series data, which allows the study of dynamic processes, is often
affected by confounding sources of signal fluctuation, including the cardiac and respiratory …