Is nicotine exposure linked to cardiopulmonary vulnerability to COVID‐19 in the general population?
The recent emergence of COVID‐19 has resulted in a worldwide crisis, with large populations
locked down and transportation links severed. While approximately 80% of infected …
locked down and transportation links severed. While approximately 80% of infected …
Beyond the channel: metabotropic signaling by nicotinic receptors
N Kabbani, RA Nichols - Trends in pharmacological sciences, 2018 - cell.com
The α7 nicotinic acetylcholine receptor (nAChR) is a ligand-gated ion channel (LGIC) that
plays an important role in cellular calcium signaling and contributes to several neurological …
plays an important role in cellular calcium signaling and contributes to several neurological …
The dropout process in life course perspective: Early risk factors at home and school
…, DR Entwisle, NS Kabbani - Teachers college …, 2001 - journals.sagepub.com
From a life course perspective, high school dropout culminates a long-term process of
disengagement from school. The present paper uses data from a representative panel of …
disengagement from school. The present paper uses data from a representative panel of …
Are nicotinic acetylcholine receptors coupled to G proteins?
… Nicotinic receptor subunits share a topology that consists of a large extracellular N-terminal
domain, four transmembrane (TM) domains, and a single large intracellular loop located …
domain, four transmembrane (TM) domains, and a single large intracellular loop located …
Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen
Standard cell culture systems impose environmental oxygen (O 2 ) levels of 20%, whereas
actual tissue O 2 levels in both developing and adult brain are an order of magnitude lower. …
actual tissue O 2 levels in both developing and adult brain are an order of magnitude lower. …
Interaction with neuronal calcium sensor NCS-1 mediates desensitization of the D2 dopamine receptor
N Kabbani, L Negyessy, R Lin… - Journal of …, 2002 - Soc Neuroscience
… Coimmunoprecipitation experiments indicate that the E120Q interacts as strongly with D2
receptors as does wild-type NCS-1 (N. Kabbani, unpublished observations). As shown in …
receptors as does wild-type NCS-1 (N. Kabbani, unpublished observations). As shown in …
Does COVID19 infect the brain? If so, smokers might be at a higher risk
COVID19 is a devastating global pandemic with epicenters in China, Italy, Spain, and now the
United States. While the majority of infected cases appear mild, in some cases, individuals …
United States. While the majority of infected cases appear mild, in some cases, individuals …
Up-regulation of neuronal calcium sensor-1 (NCS-1) in the prefrontal cortex of schizophrenic and bipolar patients
The delineation of dopamine dysfunction in the mentally ill has been a long-standing quest
of biological psychiatry. The present study focuses on a recently recognized group of …
of biological psychiatry. The present study focuses on a recently recognized group of …
Dopamine D2 and D3 receptors are linked to the actin cytoskeleton via interaction with filamin A
We have used a yeast two-hybrid approach to uncover protein interactions involving the D2-like
subfamily of dopamine receptors. Using the third intracellular loop of the D2S and D3 …
subfamily of dopamine receptors. Using the third intracellular loop of the D2S and D3 …
The dopamine D3 receptor interacts with itself and the truncated D3 splice variant d3nf: D3-D3nf interaction causes mislocalization of D3 receptors
We have generated a stable cell line expressing FLAG epitope-tagged D3 dopamine
receptors and used this cell line to study D3 receptor-protein interactions. To analyze protein …
receptors and used this cell line to study D3 receptor-protein interactions. To analyze protein …