[HTML][HTML] Utility of KL-6/MUC1 in the clinical management of interstitial lung diseases
N Ishikawa, N Hattori, A Yokoyama, N Kohno - Respiratory investigation, 2012 - Elsevier
Interstitial lung diseases (ILDs) are a diverse group of pulmonary disorders characterized by
various patterns of inflammation and fibrosis in the interstitium of the lung. Because injury …
various patterns of inflammation and fibrosis in the interstitium of the lung. Because injury …
Expression, regulation and biological actions of growth hormone (GH) and ghrelin in the immune system
N Hattori - Growth Hormone & IGF Research, 2009 - Elsevier
Immune and neuroendocrine systems have bidirectional communications. Growth hormone
(GH) and an orexigenic hormone ghrelin are expressed in various immune cells such as T …
(GH) and an orexigenic hormone ghrelin are expressed in various immune cells such as T …
Demyelinating and axonal features of Charcot–Marie–Tooth disease with mutations of myelin‐related proteins (PMP22, MPZ and Cx32): a clinicopathological study of …
N Hattori, M Yamamoto, T Yoshihara, H Koike… - Brain, 2003 - academic.oup.com
Three genes commonly causing Charcot–Marie–Tooth disease (CMT) encode myelin‐related
proteins: peripheral myelin protein 22 (PMP22), myelin protein zero (MPZ) and connexin …
proteins: peripheral myelin protein 22 (PMP22), myelin protein zero (MPZ) and connexin …
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
T Kitada, S Asakawa, N Hattori, H Matsumine… - nature, 1998 - nature.com
Parkinson's disease is a common neurodegenerative disease with complex clinical features
1 . Autosomal recessive juvenile parkinsonism (AR-JP) 2 , 3 maps to the long arm of …
1 . Autosomal recessive juvenile parkinsonism (AR-JP) 2 , 3 maps to the long arm of …
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
H Shimura, N Hattori, S Kubo, Y Mizuno, S Asakawa… - Nature …, 2000 - nature.com
… (+)FLAG vector, we ligated oligo DNAs encoding N-terminal Myc and the FLAG epitope
to the KpnI/BamHI site of pcDNA3.1(+) (Invitrogen). We amplified the cDNAs of wild-type or …
to the KpnI/BamHI site of pcDNA3.1(+) (Invitrogen). We amplified the cDNAs of wild-type or …
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
…, F Sato, M Kimura, M Komatsu, N Hattori… - Journal of Cell …, 2010 - rupress.org
Parkinson's disease (PD) is a prevalent neurodegenerative disorder. Recent identification
of genes linked to familial forms of PD such as Parkin and PINK1 (PTEN-induced putative …
of genes linked to familial forms of PD such as Parkin and PINK1 (PTEN-induced putative …
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
…, H Kawakami, S Sakoda, M Yamamoto, N Hattori… - Nature …, 2009 - nature.com
To identify susceptibility variants for Parkinson's disease (PD), we performed a genome-wide
association study (GWAS) and two replication studies in a total of 2,011 cases and 18,381 …
association study (GWAS) and two replication studies in a total of 2,011 cases and 18,381 …
Ubiquitination of a new form of α-synuclein by parkin from human brain: implications for Parkinson's disease
… will lead to accumulation of αSp22 n in ARPD (step 2b) and lack of αSp22-Ub n formation. …
Some of these αSp22-Ub n –conjugates are not efficiently processed by proteasomal …
Some of these αSp22-Ub n –conjugates are not efficiently processed by proteasomal …
[HTML][HTML] An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin
Y Imai, M Soda, H Inoue, N Hattori, Y Mizuno… - Cell, 2001 - cell.com
A putative G protein-coupled transmembrane polypeptide, named Pael receptor, was identified
as an interacting protein with Parkin, a gene product responsible for autosomal recessive …
as an interacting protein with Parkin, a gene product responsible for autosomal recessive …
Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease.
A Yoritaka, N Hattori, K Uchida… - Proceedings of the …, 1996 - National Acad Sciences
There is growing evidence that oxidative stress and mitochondrial respiratory failure with
attendant decrease in energy output are implicated in nigral neuronal death in Parkinson …
attendant decrease in energy output are implicated in nigral neuronal death in Parkinson …