The biaryl structural motif is a predominant feature in many pharmaceutically relevant and
biologically active compounds. As a result, for over a century1 organic chemists have sought …

Background This is the fourth updated Enhanced Recovery After Surgery (ERAS ® ) Society
guideline presenting a consensus for optimal perioperative care in colorectal surgery and …

Importance Enhanced Recovery After Surgery (ERAS) is a paradigm shift in perioperative
care, resulting in substantial improvements in clinical outcomes and cost savings. …

Background Human myeloproliferative disorders form a range of clonal haematological
malignant diseases, the main members of which are polycythaemia vera, essential …

Background The V617F mutation, which causes the substitution of phenylalanine for valine
at position 617 of the Janus kinase (JAK) 2 gene (JAK2), is often present in patients with …

Although talk is the fundamental material of human relations, the sociology of talk remains
undeveloped. This article presents an analysis of one kind of talk, the employment of accounts-…

A SIGNIFICANT fraction of the computer memory industry is at present involved in the
manufacture of non-volatile memory devices 1 —that is, devices which retain information when …

The basal cell nevus syndrome (BCNS) is characterized by developmental abnormalities and
by the postnatal occurrence of cancers, especially basal cell carcinomas (BCCs), the most …

The generation of high-titer, helper-free retroviruses by transient transfection has been
achieved by using the highly transfectable 293T cell line into which are stably introduced …

RNA interference (RNAi) has recently emerged as a specific and efficient method to silence
gene expression in mammalian cells either by transfection of short interfering RNAs (siRNAs…