… (H2O2) or 0.5 M sorbitol for 15 min prior to harvesting. ratio (… or absence of 1 mM hydrogen
peroxide (H2O2) for 15 min, 0.5 M sorbitol for 15 min, or 1 μM ionomycin for 5 min and AMPK …

The LKB1 tumour suppressor is a serine/threonine kinase that functions as master regulator
of cell growth, metabolism, survival and polarity. LKB1 is frequently mutated in human …

… Then, the suspensions were filtered and 20 ml of the filtrates were pipetted to 100 ml
Erlenmeyer flasks and the excess base or acid was back titrated with 0.1 M standard solutions of …

The Snf1/AMP-activated protein kinase (AMPK) family is important for metabolic regulation
and is highly conserved from yeast to mammals. The upstream kinases are also functionally …

Mitochondrial respiration is critical for cell proliferation. In addition to producing ATP,
respiration generates biosynthetic precursors, such as aspartate, an essential substrate for …

Mitochondria are critical to the governance of metabolism and bioenergetics in cancer cells
1 . The mitochondria form highly organized networks, in which their outer and inner …

The metabolic state of a cell is influenced by cell-extrinsic factors, including nutrient availability
and growth factor signaling. Here, we present extracellular matrix (ECM) remodeling as …

… We saw an increase in M+3 and M+5 labeling of citrate in SARS-CoV-2 infected cells,
indicating an increase of glucose carbon entry using PC (Supplementary Fig. 2b). The increase in …

Mitochondria are essential regulators of cellular energy and metabolism, and have a crucial
role in sustaining the growth and survival of cancer cells. A central function of mitochondria …

Altered metabolism is a hallmark of cancer growth, forming the conceptual basis for development
of metabolic therapies as cancer treatments. We performed in vivo metabolic profiling …