Laminin isoforms in development and disease
…, M Durbeej, JF Talts, M Ekblom, P Ekblom - Journal of molecular …, 2007 - Springer
… The invasive mechanism of M. leprae starts with its binding to the LG domain of the LM α2
chain [101] expressed on the muscle and peripheral nerve. This LM-pathogen complex then …
chain [101] expressed on the muscle and peripheral nerve. This LM-pathogen complex then …
Laminin isoforms and epithelial development
M Ekblom, M Falk, K Salmivirta… - Annals of the New …, 1998 - Wiley Online Library
Several different approaches suggest that basement‐membrane assembly is important for
epithelial development. Basement membranes contain isoforms of collagen IV, proteoglycans, …
epithelial development. Basement membranes contain isoforms of collagen IV, proteoglycans, …
[PDF][PDF] Critical role of thrombopoietin in maintaining adult quiescent hematopoietic stem cells
…, J Antonchuk, R Månsson, LA Thoren, M Ekblom… - Cell stem cell, 2007 - cell.com
The role of cytokines in regulation of hematopoietic stem cells (HSCs) remains poorly
understood. Herein we demonstrate that thrombopoietin (THPO) and its receptor, MPL, are …
understood. Herein we demonstrate that thrombopoietin (THPO) and its receptor, MPL, are …
Clonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapy
S Mustjoki, M Ekblom, TP Arstila, I Dybedal… - Leukemia, 2009 - nature.com
Dasatinib, a broad-spectrum tyrosine kinase inhibitor (TKI), predominantly targets BCR-ABL
and SRC oncoproteins and also inhibits off-target kinases, which may result in unexpected …
and SRC oncoproteins and also inhibits off-target kinases, which may result in unexpected …
Mono/oligoclonal T and NK cells are common in chronic myeloid leukemia patients at diagnosis and expand during dasatinib therapy
…, V Juvonen, V Kairisto, M Ekblom… - Blood, The Journal …, 2010 - ashpublications.org
In a proportion of patients with chronic myeloid leukemia (CML) being treated with dasatinib,
we recently observed large granular lymphocyte (LGL) expansions carrying clonal T-cell …
we recently observed large granular lymphocyte (LGL) expansions carrying clonal T-cell …
Deep and superficial abdominal muscle activation during trunk stabilization exercises with and without instruction to hollow
A Bjerkefors, MM Ekblom, K Josefsson, A Thorstensson - Manual Therapy, 2010 - Elsevier
The deepest muscle of the human ventro-lateral abdominal wall, the Transversus Abdominis
(TrA), has been ascribed a specific role in spine stabilization, which has motivated special …
(TrA), has been ascribed a specific role in spine stabilization, which has motivated special …
Tyrosine kinase inhibitor usage, treatment outcome, and prognostic scores in CML: report from the population-based Swedish CML registry
…, M Brune, A Dreimane, M Ekblom… - Blood, The Journal …, 2013 - ashpublications.org
Clinical management guidelines on malignant disorders are generally based on data from
clinical trials with selected patient cohorts. In Sweden, more than 95% of all patients …
clinical trials with selected patient cohorts. In Sweden, more than 95% of all patients …
Role of mesenchymal nidogen for epithelial morphogenesis in vitro
P Ekblom, M Ekblom, L Fecker, G Klein… - …, 1994 - journals.biologists.com
Recent biochemical studies suggested that the extracellular matrix protein nidogen is a binding
molecule linking together basement membrane components. We studied its expression …
molecule linking together basement membrane components. We studied its expression …
Laminin isoform–specific promotion of adhesion and migration of human bone marrow progenitor cells
…, P Ekblom, SE Jacobsen, M Ekblom - Blood, The Journal …, 2003 - ashpublications.org
Laminins are αβγ heterotrimeric extracellular proteins that regulate cellular functions by
adhesion to integrin and nonintegrin receptors. Laminins containing α4 and α5 chains are …
adhesion to integrin and nonintegrin receptors. Laminins containing α4 and α5 chains are …
[PDF][PDF] Low/negative expression of PDGFR-α identifies the candidate primary mesenchymal stromal cells in adult human bone marrow
Human bone marrow (BM) contains a rare population of nonhematopoietic mesenchymal
stromal cells (MSCs), which are of central importance for the hematopoietic microenvironment. …
stromal cells (MSCs), which are of central importance for the hematopoietic microenvironment. …