Systems medicine has a mechanism-based rather than a symptom- or organ-based approach
to disease and identifies therapeutic targets in a nonhypothesis-driven manner. In this …

Heme oxygenase 1 (HO-1) is induced by oxidative or nitrosative stress, cytokines and other
mediators produced during inflammatory processes, likely as part of a defence system in …

A review summarizing current knowledge and including a table showing plant sources of 11
different groups of flavonoids (flavones, flavonols, flavanones, dihydroflavonols, …

The last decade has seen a sharp increase in the number of scientific publications describing
physiological and pathological functions of extracellular vesicles (EVs), a collective term …

Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …

A group of flavonoids isolated from medicinal plants and which are selective inhibitors of
lipoxygenase activityin vitro: sideritoflavone, cirsiliol, hypolaetin-8-O-β-d-glucoside, hypolaetin, …

Polymethoxylated flavones and C-glycosyl derivatives isolated from medicinal plants besides
other flavonoid compounds were studied for their influence on lipid peroxidation induced …

… glycoside are not of the aspirin-like type (Alcaraz & Hoult 1985a). The two compounds
also exerted inhibitory effects on the plant 15-lipoxygenase enzyme (Alcaraz & Hoult 1985b). …

The antiperoxidative effects of 35 phenolic compounds, most of them belonging to the flavonoid
class, were investigated using CCl 4 -induced peroxidation of rat liver microsomes. This …

1. A series of flavonoids isolated from Indian medicinal plants: kaempferol-3-O-galactoside,
hispidulin, nepetin, scutellarein, scutellarein-7-O-glucuronide, hibifolin and morelloflavone …