User profiles for M. B. Thygesen
Mikkel Boas ThygesenDepartment of Chemistry, University of Copenhagen Verified email at chem.ku.dk Cited by 3333 |
Solid-phase chemical tools for glycobiology
K Larsen, MB Thygesen, F Guillaumie, WGT Willats… - Carbohydrate …, 2006 - Elsevier
Techniques involving solid supports have played crucial roles in the development of genomics,
proteomics, and in molecular biology in general. Simularly, methods for immobilization or …
proteomics, and in molecular biology in general. Simularly, methods for immobilization or …
Chemoselective reactions for the synthesis of glycoconjugates from unprotected carbohydrates
…, KJ Jensen, MB Thygesen - …, 2017 - Wiley Online Library
Glycobiology is the comprehensive biological investigation of carbohydrates. The study of the
role and function of complex carbohydrates often requires the attachment of carbohydrates …
role and function of complex carbohydrates often requires the attachment of carbohydrates …
Receptor-mediated exopolysaccharide perception controls bacterial infection
Surface polysaccharides are important for bacterial interactions with multicellular organisms,
and some are virulence factors in pathogens. In the legume–rhizobium symbiosis, bacterial …
and some are virulence factors in pathogens. In the legume–rhizobium symbiosis, bacterial …
Legume receptors perceive the rhizobial lipochitin oligosaccharide signal molecules by direct binding
…, S Thirup, CW Ronson, MB Thygesen… - Proceedings of the …, 2012 - National Acad Sciences
Lipochitin oligosaccharides called Nod factors function as primary rhizobial signal molecules
triggering legumes to develop new plant organs: root nodules that host the bacteria as …
triggering legumes to develop new plant organs: root nodules that host the bacteria as …
Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy) phenylmethyl) carbamide (2R, 3R) …
…, TR Ott, ES Burstein, AK Uldam, MB Thygesen… - … of Pharmacology and …, 2006 - ASPET
The in vitro and in vivo pharmacological properties of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide
(2R,3R)-…
(2R,3R)-…
[HTML][HTML] A combination of chitooligosaccharide and lipochitooligosaccharide recognition promotes arbuscular mycorrhizal associations in Medicago truncatula
Plants associate with beneficial arbuscular mycorrhizal fungi facilitating nutrient acquisition.
Arbuscular mycorrhizal fungi produce chitooligosaccharides (COs) and lipo-…
Arbuscular mycorrhizal fungi produce chitooligosaccharides (COs) and lipo-…
Impact of Chain Length on Antibacterial Activity and Hemocompatibility of Quaternary N-Alkyl and N,N-Dialkyl Chitosan Derivatives
…, KK Sørensen, MB Thygesen… - …, 2015 - ACS Publications
A highly efficient method for chemical modification of chitosan biopolymers by reductive
amination to yield N,N-dialkyl chitosan derivatives was developed. The use of 3,6-O-di-tert-…
amination to yield N,N-dialkyl chitosan derivatives was developed. The use of 3,6-O-di-tert-…
Ligand-recognizing motifs in plant LysM receptors are major determinants of specificity
…, N de Jong, M Vinther, M Kamble, MB Thygesen… - Science, 2020 - science.org
Plants evolved lysine motif (LysM) receptors to recognize and parse microbial elicitors and
drive intracellular signaling to limit or facilitate microbial colonization. We investigated how …
drive intracellular signaling to limit or facilitate microbial colonization. We investigated how …
Antimicrobial peptide shows enhanced activity and reduced toxicity upon grafting to chitosan polymers
Here we report that grafting of a short antimicrobial peptide, anoplin, to chitosan polymers is
a strategy for abolishing the hemolytic propensity, and at the same time increasing the …
a strategy for abolishing the hemolytic propensity, and at the same time increasing the …
Switching of bacterial adhesion to a glycosylated surface by reversible reorientation of the carbohydrate ligand
…, I Stamer, MB Thygesen… - Angewandte Chemie …, 2014 - Wiley Online Library
The surface recognition in many biological systems is guided by the interaction of
carbohydrate‐specific proteins (lectins) with carbohydrate epitopes (ligands) located within the …
carbohydrate‐specific proteins (lectins) with carbohydrate epitopes (ligands) located within the …