[HTML][HTML] A perspective on potential antibody-dependent enhancement of SARS-CoV-2

AM Arvin, K Fink, MA Schmid, A Cathcart, R Spreafico… - Nature, 2020 - nature.com
Antibody-dependent enhancement (ADE) of disease is a general concern for the development
of vaccines and antibody therapies because the mechanisms that underlie antibody …

Instructive cytokine signals in dendritic cell lineage commitment

MA Schmid, D Kingston, S Boddupalli… - Immunological …, 2010 - Wiley Online Library
… to inflamed lymphoid organs (MA Schmid, unpublished data). Future research will show
which factors influence the specific localization and migratory behavior of DC progenitors. …

[HTML][HTML] Dendritic cells in dengue virus infection: targets of virus replication and mediators of immunity

MA Schmid, MS Diamond, E Harris - Frontiers in immunology, 2014 - frontiersin.org
Schmid)]. The authors declare no competing financial interests. … Schmid MA, Harris E.
Monocyte recruitment to the dermis and differentiation to dendritic cells increases the targets for …

Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms

…, F Benigni, R Abdelnabi, SYC Foo, MA Schmid… - Science, 2020 - science.org
Efficient therapeutic options are needed to control the spread of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) that has caused more than 922,000 fatalities as of 13 …

Identification of clonogenic common Flt3+M-CSFR+ plasmacytoid and conventional dendritic cell progenitors in mouse bone marrow

N Onai, A Obata-Onai, MA Schmid, T Ohteki… - Nature …, 2007 - nature.com
Lymphoid tissue plasmacytoid and conventional dendritic cells (DCs) are continuously
regenerated from hematopoietic stem cells. The cytokine dependence and biology of …

[HTML][HTML] Broad sarbecovirus neutralization by a human monoclonal antibody

…, SYC Foo, C Havenar-Daughton, MA Schmid… - Nature, 2021 - nature.com
The recent emergence of SARS-CoV-2 variants of concern 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 – 10
and the recurrent spillovers of coronaviruses 11 , 12 into the human population highlight the …

Imprinted antibody responses against SARS-CoV-2 Omicron sublineages

…, M Giurdanella, C Saliba, B Guarino, MA Schmid… - Science, 2022 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages carry
distinct spike mutations resulting in escape from antibodies induced by previous infection or …

The dual function monoclonal antibodies VIR-7831 and VIR-7832 demonstrate potent in vitro and in vivo activity against SARS-CoV-2

…, C Havenar-Daughton, FA Lempp, D Ma, MA Schmid… - biorxiv, 2021 - biorxiv.org
VIR-7831 and VIR-7832 are dual action monoclonal antibodies (mAbs) targeting the spike
glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). VIR-7831 …

[HTML][HTML] Neutralization, effector function and immune imprinting of Omicron variants

…, C Stewart, H Chu, H Bourhy, MA Schmid… - Nature, 2023 - nature.com
Currently circulating SARS-CoV-2 variants have acquired convergent mutations at hot spots
in the receptor-binding domain 1 (RBD) of the spike protein. The effects of these mutations …

The concerted action of GM-CSF and Flt3-ligand on in vivo dendritic cell homeostasis

D Kingston, MA Schmid, N Onai… - Blood, The Journal …, 2009 - ashpublications.org
Dendritic cell (DC) development is efficiently supported by Flt3-ligand or GM-CSF in vitro,
and lymphoid-organ DC maintenance in vivo is critically dependent on Flt3-ligand. However, …