The importance of glucocorticoids in alcoholdependence and neurotoxicity
AK Rose, SG Shaw, MA Prendergast… - Alcoholism: Clinical …, 2010 - Wiley Online Library
Alterations in hypothalamo‐pituitary adrenal (HPA) function have been described in alcoholics
and in rodents after chronic alcohol consumption but the role of glucocorticoids in alcohol …
and in rodents after chronic alcohol consumption but the role of glucocorticoids in alcohol …
Sex differences in neuroadaptation to alcohol and withdrawal neurotoxicity
…, AR Reynolds, JN Berry, MA Prendergast - … -European Journal of …, 2013 - Springer
… Prendergast … Barron S, Mulholland PJ, Littleton JM, Prendergast MA (2008) Age and
gender differences in response to neonatal ethanol withdrawal and polyamine challenge in …
gender differences in response to neonatal ethanol withdrawal and polyamine challenge in …
Functional characterization of the novel neuronal nicotinic acetylcholine receptor ligand GTS-21 in vitro and in vivo
…, DJB Kim, KC Marsh, A O'Neill, MA Prendergast… - Pharmacology …, 1997 - Elsevier
[2, 4]-Dimethoxybenzylidene anabaseine dihydrochloride (GTS-21), a compound that interacts
with rat neuronal nicotinic acetylcholine receptors (nAChRs), was evaluated using human …
with rat neuronal nicotinic acetylcholine receptors (nAChRs), was evaluated using human …
Proximal junctional acute collapse cranial to multi-level lumbar fusion: a cost analysis of prophylactic vertebral augmentation
RA Hart, MA Prendergast, WG Roberts, GM Nesbit… - The Spine Journal, 2008 - Elsevier
BACKGROUND CONTEXT: Limited data are available regarding incidence of proximal
junctional acute collapse after multilevel lumbar spine fusion. There are no data regarding the …
junctional acute collapse after multilevel lumbar spine fusion. There are no data regarding the …
Critical needs in drug discovery for cessation of alcohol and nicotine polysubstance abuse
…, MT Bardo, LP Dwoskin, MA Prendergast… - Progress in Neuro …, 2016 - Elsevier
Polysubstance abuse of alcohol and nicotine has been overlooked in our understanding of
the neurobiology of addiction and especially in the development of novel therapeutics for its …
the neurobiology of addiction and especially in the development of novel therapeutics for its …
Acamprosate inhibits the binding and neurotoxic effects of trans‐ACPD, suggesting a novel site of action at metabotropic glutamate receptors
BR Harris, MA Prendergast, DA Gibson… - Alcoholism: Clinical …, 2002 - Wiley Online Library
Background Several reported effects of acamprosate within the glutamatergic system could
result from interactions with metabotropic glutamate receptors (mGluRs). The following …
result from interactions with metabotropic glutamate receptors (mGluRs). The following …
Repeated exposures to subthreshold doses of chlorpyrifos in rats: hippocampal damage, impaired axonal transport, and deficits in spatial learning
…, DW Sickles, A Sood, MA Prendergast - … of Pharmacology and …, 2003 - ASPET
Organophosphorus (OP) compounds are detectable in the environment for years after use
and endanger many populations. Although the effects of acutely toxic doses of many OP …
and endanger many populations. Although the effects of acutely toxic doses of many OP …
Chronic, intermittent exposure to chlorpyrifos in rats: protracted effects on axonal transport, neurotrophin receptors, cholinergic markers, and information processing
…, LN Williamson, MG Bartlett, MA Prendergast… - … of Pharmacology and …, 2007 - ASPET
Persistent behavioral abnormalities have been commonly associated with acute organophosphate
(OP) pesticide poisoning; however, relatively little is known about the consequences …
(OP) pesticide poisoning; however, relatively little is known about the consequences …
Selective vulnerability of hippocampal cornu ammonis 1 pyramidal cells to excitotoxic insult is associated with the expression of polyamine-sensitive N-methyl-D …
…, JR Pauly, PJ Mulholland, MA Prendergast - Neuroscience, 2010 - Elsevier
Excess glutamate release and stimulation of post-synaptic glutamatergic receptors have been
implicated in the pathophysiology of many neurological diseases. The hippocampus, and …
implicated in the pathophysiology of many neurological diseases. The hippocampus, and …
Lesions of the nucleus paragigantocellularis: effects on mating behavior in male rats
DP Yells, SE Hendricks, MA Prendergast - Brain Research, 1992 - Elsevier
We evaluated the effects of bilateral radio-frequency lesions of the paragigantocellular (PGi)
reticular nucleus in the ventral medulla on male rat copulatory behavior. In Experiment 1, …
reticular nucleus in the ventral medulla on male rat copulatory behavior. In Experiment 1, …