Free-radical scavenging action of medicinal herbs from Ghana: Thonningia sanguinea on experimentally-induced liver injuries

MA Gyamfi, M Yonamine, Y Aniya - General Pharmacology: The Vascular …, 1999 - Elsevier
The antioxidant action of medicinal herbs used in Ghana for treating various ailments was
evaluated in vitro and in vivo. Five plants, Desmodium adscendens, Indigofera arrecta, Trema …

Pathogenesis of alcoholic liver disease: the role of nuclear receptors

MA Gyamfi, YJY Wan - Experimental Biology and Medicine, 2010 - journals.sagepub.com
Ethanol consumption causes fatty liver, which can lead to inflammation, fibrosis, cirrhosis and
even liver cancer. The molecular mechanisms by which ethanol exerts its damaging effects …

NF-E2-related factor 2 inhibits lipid accumulation and oxidative stress in mice fed a high-fat diet

Y Tanaka, LM Aleksunes, RL Yeager, MA Gyamfi… - … of Pharmacology and …, 2008 - ASPET
NF-E2-related factor 2 (Nrf2) is a transcription factor that is activated by oxidative stress and
electrophiles that regulates the expression of numerous detoxifying and antioxidant genes. …

Evaluation of CYP2A6 genetic polymorphisms as determinants of smoking behavior and tobacco-related lung cancer risk in male Japanese smokers

…, H Yamazaki, T Saito, K Kiyotani, MA Gyamfi… - …, 2004 - academic.oup.com
We reported previously that subjects homozygous for the cytochrome P450 2A6 ( CYP2A6 )
* 4 have a lower risk of lung cancer. The purpose of this study was to clarify whether or not …

Antioxidant properties of Thonningianin A, isolated from the African medicinal herb, Thonningia sanguinea

MA Gyamfi, Y Aniya - Biochemical Pharmacology, 2002 - Elsevier
The antioxidant properties of Thonningianin A (Th A), an ellagitannin, isolated from the
methanolic extract of the African medicinal herb, Thonningia sanguinea were studied using the …

[HTML][HTML] Role of pregnane X receptor in obesity and glucose homeostasis in male mice

…, EM Awumey, FJ Gonzalez, MA Gyamfi - Journal of Biological …, 2014 - ASBMB
Clinical obesity is a complex metabolic disorder affecting one in three adults. Recent reports
suggest that pregnane X receptor (PXR), a xenobiotic nuclear receptor important for …

Inhibition of glutathione S-transferases by thonningianin A, isolated from the African medicinal herb, Thonningia sanguinea, in vitro

MA Gyamfi, II Ohtani, E Shinno, Y Aniya - Food and Chemical Toxicology, 2004 - Elsevier
There is evidence that increased expression of glutathione S-transferase (EC: 2.5.1.18, GST)
is involved in resistance of tumor cells against chemotherapeutic agents. In this study we …

[HTML][HTML] TNFAIP8 regulates autophagy, cell steatosis, and promotes hepatocellular carcinoma cell proliferation

S Niture, MA Gyamfi, M Lin, U Chimeh, X Dong… - Cell death & …, 2020 - nature.com
… , 3-MA for 18 h and transfected with EV and TNFAIP8-Myc plasmid for 24 h in the presence
of 3-MA … h, i Effect of TNFAIP8 overexpression and 3-MA on LC3β related puncta formation in …

Antioxidant and hepatoprotective actions of the medicinal herb Artemisia campestris from the Okinawa Islands

…, M Shimoji, M Kohatsu, MA Gyamfi… - Biological and …, 2000 - jstage.jst.go.jp
The antioxidant action of Artemisia camprestris was examined in vitro and in vivo. A water
extract of A. campestris showed a strong scavenging action of 1, 1-diphenyl-2-picrylhydrazyl (…

[HTML][HTML] MicroRNA-483-5p inhibits hepatocellular carcinoma cell proliferation, cell steatosis, and fibrosis by targeting PPARα and TIMP2

S Niture, S Gadi, Q Qi, MA Gyamfi, RS Varghese… - Cancers, 2023 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is the fifth leading and highly aggressive
lethal liver cancer. The most common cause of HCC is liver cirrhosis because of multiple …