Oxidative stress-induced DNA damage by particulate air pollution

L Risom, P Møller, S Loft - Mutation Research/Fundamental and Molecular …, 2005 - Elsevier
Exposure to ambient air particulate matter (PM) is associated with pulmonary and cardiovascular
diseases and cancer. The mechanisms of PM-induced health effects are believed to …

Air pollution, oxidative damage to DNA, and carcinogenesis

…, L Forchhammer, EV Bräuner, PH Danielsen, L Risom… - Cancer letters, 2008 - Elsevier
There is growing concern that air pollution exposure increases the risk of lung cancer. The
mechanism of action is related to particle-induced oxidative stress and oxidation of DNA. …

Guidelines for the genetic diagnosis of hereditary recurrent fevers

…, S Ozen, L Phylactou, L Risom… - Annals of the …, 2012 - ard.bmj.com
Hereditary recurrent fevers (HRFs) are a group of monogenic autoinflammatory diseases
characterised by recurrent bouts of fever and serosal inflammation that are caused by …

Oxidatively Damaged DNA in Rats Exposed by Oral Gavage to C60 Fullerenes and Single-Walled Carbon Nanotubes

JK Folkmann, L Risom, NR Jacobsen… - Environmental …, 2009 - ehp.niehs.nih.gov
Background C 60 fullerenes and single-walled carbon nanotubes (SWCNT) are projected to
be used in medicine and consumer products with potential human exposure. The …

A mutation update on the LDS‐associated genes TGFB2/3 and SMAD2/3

…, E El‐Khoury, S Parkash, B Diness, L Risom… - Human …, 2018 - Wiley Online Library
The Loeys–Dietz syndrome (LDS) is a connective tissue disorder affecting the cardiovascular,
skeletal, and ocular system. Most typically, LDS patients present with aortic aneurysms …

Biomarkers of oxidative damage to DNA and repair

…, L Mikkelsen, L Risom, L Forchhammer… - 2008 - portlandpress.com
Oxidative-stress-induced damage to DNA includes a multitude of lesions, many of which are
mutagenic and have multiple roles in cancer and aging. Many lesions have been …

Inflammatory and genotoxic effects of diesel particles in vitro and in vivo

M Dybdahl, L Risom, J Bornholdt, H Autrup… - … /Genetic Toxicology and …, 2004 - Elsevier
Recent studies have identified an indirect genotoxicity pathway involving inflammation as
one of the mechanisms underlying the carcinogenic effects of air pollution/diesel exhaust …

Oxidative DNA damage and defence gene expression in the mouse lung after short-term exposure to diesel exhaust particles by inhalation

L Risom, M Dybdahl, J Bornholdt, U Vogel… - …, 2003 - academic.oup.com
… steel chamber with a volume of 18 l. A microfeeder aerosoled constant flow of DEP into a
nozzle that atomised the DEP into fine aerosol in a flow of 25 l/min. The concentration of …

DNA adduct formation and oxidative stress in colon and liver of Big Blue® rats after dietary exposure to diesel particles

M Dybdahl, L Risom, P Møller, H Autrup… - …, 2003 - academic.oup.com
Exposure to diesel exhaust particles (DEP) via the gastrointestinal route may impose risk of
cancer in the colon and liver. We investigated the effects of DEP given in the diet to Big Blue…

Histologic evaluation of new attachment in humans: a preliminary report

…, B Peltzman, E Romberg, L Risom - Journal of …, 1985 - Wiley Online Library
… fr0rrie L^FDBA used in this investigation is obtained Sit fs'avy Tissue Bank, Naval Medical …
m l .09 to 2.32 mm and a grand mean of 1.81 oirr,) sma" amount of new bone formation (0.005 …